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Gloves and Socks Syndrome
Aka: Gloves and Socks Syndrome
- Causes
- Parvovirus B19 (Fifth Disease)
- Hepatitis BVirus
- Cytomegalovirus
- Epstein-Barr Virus (Mononucleosis)
- Human Herpesvirus 6
- Measles
- Coxsackievirus B
- Kawasaki Disease
- Drug eruption
- Symptoms: Usually asymptomatic
- Arthralgia
- Fever
- Signs
- Initial
- Symmetric painful erythema, edema of hands and feet
- Sharply demarcated at wrists and ankles
- May involve cheeks, elbow, knees and genitalia
- Later
- Petechiae or Purpura
- Later
- Vesicles or bullae
- Skin sloughing
- Course
- Resolves spontaneously in 1-3 weeks
- Does not result in residual scarring
- References
- Alfadley (2003) J Am Acad Dermatol 48:941-4 [PubMed]