Hematology and Oncology Book

Anemia

Cancer

Coagulopathy

Platelet Disorders

Hemoglobinopathies

Hemolytic Disorders

Pathology and Laboratory Medicine

Lymphatic Disorders

Blood Transfusion

Obstetrics Chapter related topics

//fpnotebook.com/

Transfusion Associated Circulatory Overload

Aka: Transfusion Associated Circulatory Overload, Transfusion Related Circulatory Overload, TACO
  1. See Also
    1. Transfusion Complication
    2. Transfusion-Related Acute Lung Injury (TRALI)
  2. Epidemiology
    1. Incidence: 1 to 8% of transfusions
    2. Leading cause of transfusion-associated mortality
  3. Pathophysiology
    1. Blood Product transfusion volume results in Cardiogenic Pulmonary Edema
    2. Each unit of Blood Product ranges from 150 to 300 ml and initially, most of this remains intravascular
    3. Infused volumes may be large when multiple units are transfused
  4. Risk Factors
    1. Cardiomyopathy or chronic Congestive Heart Failure
    2. Chronic Kidney Disease
    3. Compensated Anemia
    4. Baseline volume overload
    5. Cancer
    6. Anticoagulation Reversal with plasma
    7. Very young (infants) and elderly
  5. Differential Diagnosis
    1. Transfusion-Related Acute Lung Injury (TRALI)
  6. Signs
    1. Fever
    2. Dyspnea
    3. Tachypnea
    4. Tachycardia
    5. Hypoxemia
    6. Hypertension
    7. Cardiogenic Pulmonary Edema related findings (distinguishes TACO from TRALI)
      1. Peripheral Edema
      2. Jugular Venous Distention
  7. Imaging: Chest XRay
    1. Bilateral Pulmonary Infiltrates
  8. Labs
    1. NT-BNP elevated
      1. Contrast with normal level in TRALI
  9. Management
    1. Manage as acute Cardiogenic Shock
    2. Supportive Care
  10. Prevention
    1. Slow transfusion to >4 hours
    2. Decrease transfusion volume
  11. References
    1. Raval (2020) Am Fam Physician 102(1):30-8 [PubMed]

Transfusion-related circulatory overload (C1739101)

Concepts Sign or Symptom (T184)
English Transfusion-related circulatory overload
Dutch transfusiegerelateerde circulatoire 'overload'
French Surcharge circulatoire liée à la transfusion
German Transfusionsbedingte Ueberladung des Kreislaufsystems
Italian Sovraccarico circolatorio da trasfusione
Portuguese Sobrecarga circulatória relacionada com transfusão
Spanish Sobrecarga circulatoria post-transfusional
Japanese 輸血に伴う循環過負荷, ﾕｹﾂﾆﾄﾓﾅｳｼﾞｭﾝｶﾝｶﾌｶ
Czech Přetížení oběhového systému souvisící s trasfúzí
Hungarian Transzfúzióval összefüggő keringés túlterhelés
Sources
Derived from the NIH UMLS (Unified Medical Language System)


You are currently viewing the original 'fpnotebook.com\legacy' version of this website. Internet Explorer 8.0 and older will automatically be redirected to this legacy version.

If you are using a modern web browser, you may instead navigate to the newer desktop version of fpnotebook. Another, mobile version is also available which should function on both newer and older web browsers.

Please Contact Me as you run across problems with any of these versions on the website.

Navigation Tree