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Streptokinase
Aka: Streptokinase- See Also
- Dose
- Streptokinase 1.5 million units over 60 minutes
- Premedication
- Hydrocortisone 100 mg IV
- Diphenhydramine 25 mg IV
- Contraindications: Conditions in which streptococcal Antibody is more likely to be present (risk of severe Allergic Reaction)
- Prior exposure to Streptokinase
- Recent streptococcal infection
- Benefits
- Cost: $200
- Lasts longer than T-PA (duration 24 hours)
- Less bleeding risk
- Probably less risk than T-PA in over age 75
Streptokinase (C0038418) |
|
|---|---|
| Definition (MSH) | Streptococcal fibrinolysin . An enzyme produced by hemolytic streptococci. It hydrolyzes amide linkages and serves as an activator of plasminogen. It is used in thrombolytic therapy and is used also in mixtures with streptodornase (STREPTODORNASE AND STREPTOKINASE). EC 3.4.-. |
| Definition (CSP) | nonEC; enzyme elaborated by hemolytic streptococci which produces fibrinolysis by activating plasminogen to plasmin; it is used as a thrombolytic agent. |
| Concepts | Pharmacologic Substance (T121) , Amino Acid, Peptide, or Protein (T116) , Enzyme (T126) |
| MSH | D013300 |
| SnomedCT | 319810009, 395889004, 20847002 |
| LNC | LP16489-4, MTHU021627 |
| English | Streptokinase, streptokinase, streptokinase (medication), Streptokinase [Chemical/Ingredient], SK - Streptokinase, Streptokinase (product), Streptokinase (substance), Streptokinase preparation (substance), STREPTOKINASE, Streptokinase preparation, Streptokinase agent (substance), Streptokinase agent |
| Spanish | preparado de estreptoquinasa (sustancia), preparado de estreptoquinasa, estreptoquinasa (producto), estreptocinasa, estreptoquinasa, estreptocinasa (sustancia), estreptokinasa, estreptoquinasa (sustancia), estreptocinasa (producto), Estreptocinasa, estreptokinasa (producto), estreptokinasa (sustancia), Estreptoquinasa |
| Swedish | Streptokinas |
| Czech | streptokinasa |
| Finnish | Streptokinaasi |
| Russian | NEITRAL'NAIA PROTEINAZA STAPHYLOCOCCUS AUREUS, STREPTOKINAZA, STREPTAZA, НЕЙТРАЛЬНАЯ ПРОТЕИНАЗА STAPHYLOCOCCUS AUREUS, СТРЕПТАЗА, СТРЕПТОКИНАЗА |
| Japanese | ストレプトキナーゼ |
| Croatian | STREPTOKINAZA |
| Polish | Streptokinaza |
| Norwegian | Not Translated[Streptokinase] |
| French | Streptokinase |
| German | Streptokinase |
| Italian | Streptochinasi |
| Portuguese | Estreptoquinase |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
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