Hematology and Oncology Book

Hemolytic Disorders

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Medications in G6PD Deficiency

Aka: Medications in G6PD Deficiency, Drug Induced Hemolysis in Glucose-6-Phosphate Dehydrogenase Deficiency, Drug Induced Hemolysis in G6PD
  1. See Also
    1. G6PD Deficiency
  2. Medications: Avoid in G6PD Deficiency
    1. Anti-parasitic Agents
      1. Primaquine
      2. Pamaquine
      3. Niridazole (Ambilhar)
    2. Sulfonamides
      1. Sulfacetamide
      2. Sulfanilamide
      3. Sulfapyridine
      4. Sulfasalazine
    3. Anti-Bacterials
      1. Furazolidone (Furoxone)
      2. Nitrofurantoin (Macrobid, Furadantin)
      3. Nalidixic Acid
      4. Diaminodiphenyl Sulfone (Dapsone)
      5. Mafenide Cream (Sulfamylon)
    4. Analgesics
      1. Phenacetin
      2. Acetanilid
      3. Phenazopyridine (Pyridium)
    5. Miscellaneous
      1. Quinine
      2. Flutamide (Eulexin)
      3. Methylene Blue
      4. Rasburicase (Elitek)
      5. Isobutyl Nitrite
  3. Medications: Use Only With Caution in Mild G6PD Deficiency (NOT with Class I or Nonspherocytic Hemolytic Anemia)
    1. General
      1. Considered safe with caution in mild G6PD (Class 3 G6PD)
      2. Do NOT use in Nonspherocytic Hemolytic Anemia
    2. Analgesics
      1. Acetaminophen
      2. Aspirin
      3. Aurodex
    3. Cardiovascular Agents
      1. Procainamide
      2. Quinidine
    4. Neurologic Agents
      1. Trihexyphenidyl
      2. Levodopa
      3. Phenytoin
    5. Antibiotics
      1. Chloramphenicol
      2. Chloroquine
      3. Isoniazid
      4. Probenecid
      5. Proguanil
      6. Pyrimethamine
      7. Streptomycin
      8. Sulfadiazine
      9. Sulfacytine
      10. Sulfamethoxazole (e.g. Septra, Bactrim)
      11. Sulfisoxazole
      12. Trimethoprim
    6. Antihistamines and Anticholinergics
      1. Antazoline
      2. Benzhexol (Trihexyphenidyl, Artane)
      3. Diphenhydramine (Benadryl)
      4. Tripelennamine (Pyribenzamine)
    7. Miscellaneous
      1. Antipyrine
      2. Ascorbic Acid (Vitamin C)
      3. Vitamin K
      4. Colchicine
      5. Glyburide
      6. Quinine
  4. References
    1. Bubp (2015) PT +40(9):572-4 +PMID: 26417175 [PubMed]

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