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Hematology Medications in Pregnancy
Aka: Hematology Medications in Pregnancy, Oncology Medications in Pregnancy
- See Also
- Medications in Pregnancy
- Background
- Pregnancy Categories will be replaced on medication bottles with specific warnings and precautions by 2020 in U.S.
- http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm425317.htm
- Although FDA Pregnancy Categories are no longer FDA designated, they are included here
- As of 2018, succinct guidance (to replace ABCDX) on specific drugs in pregnancy is lacking
- Class B: No risk in controlled animal studies
- Iron Sulfate - Not in Briggs (1998)
- Anticoagulants
- Enoxaparin (Lovenox)
- Dalteparin (Fragmin)
- Danaparoid (Orgaran)
- Heparin
- Class C: Small risk in controlled animal studies
- Antiplatelet Medications
- Clopidogrel (Plavix) - not in Briggs (1998)
- Dipyridamole (Persantine)
- Ticlopidine (Ticlid) - not in Briggs (1998)
- Chemotherapeutics
- Asparaginase
- Dacarbazine
- Dactinomycin
- Interferon alfa
- Class D: Strong evidence of risk to the human fetus
- Chemotherapeutics
- Bleomycin
- Cisplatin
- Cyclophosphamide
- Cytarabine
- Daunorubicin
- Doxorubicin
- Etoposide
- Fluorouracil
- Hydroxyurea
- Melphalan
- Mercaptopurine
- Methotrexate
- Plicamycin
- Tamoxifen
- Vinblastine
- Vincristine
- Miscellaneous Agents
- EDTA - Not in Briggs (1998)
- Penicillamine
- Anticoagulants
- Coumadin (Warfarin)
- Dicumarol
- Class X: Very high risk to the human fetus
- Leuprolide (Lupron)
- Aminopterin
- References
- Briggs (1998) Drugs in Pregnancy and Lactation, 5th ed
- Larimore (2000) Prim Care 27(1):35-53 [PubMed]