Hematology and Oncology Book



Serum Ferritin

Aka: Serum Ferritin, Ferritin
  1. See Also
    1. Iron Deficiency Anemia
    2. Hemochromatosis
    3. Acute Phase Reactant
  2. Indications
    1. Evaluation for Iron Deficiency Anemia
    2. Screening for Hemochromatosis
  3. Physiology
    1. Indicator of total body iron stores
      1. Most reliable indicator other than Bone Marrow
    2. Acute phase reactant
  4. Interpretation: Normal
    1. Range: 18-300 ng/ml
  5. Interpretation: Increased
    1. Inflammatory states
    2. Hyperthyroidism
    3. Liver disease (necrotic hepatocytes)
    4. Hodgkin's Lymphoma and Non-Hodgkin's Lymphoma
    5. Leukemia
    6. Breast Cancer
    7. Neuroblastomas
    8. Hemochromatosis
    9. Iron Supplementation
    10. Still's Disease (very high, Ferritin >5000)
  6. Interpretation: Decreased
    1. Iron Deficiency Anemia

Ferritin (C0015879)

Definition (CHV) a protein that stores iron
Definition (CHV) a protein that stores iron
Definition (NCI) An iron protein complex, containing up to 23% iron, formed by the union of ferric iron with apoferritin; it is found in the intestinal mucosa, spleen, bone marrow, reticulocytes, and liver, and regulates iron storage and transport from the intestinal lumen to plasma.
Definition (CSP) iron containing protein complex that is formed by a combination of ferric iron with the protein apoferritin; one of the chief forms in which iron is stored in the body.
Definition (MSH) Iron-containing proteins that are widely distributed in animals, plants, and microorganisms. Their major function is to store IRON in a nontoxic bioavailable form. Each ferritin molecule consists of ferric iron in a hollow protein shell (APOFERRITINS) made of 24 subunits of various sequences depending on the species and tissue types.
Concepts Pharmacologic Substance (T121) , Biologically Active Substance (T123) , Amino Acid, Peptide, or Protein (T116)
MSH D005293
SnomedCT 32789000
LNC LP15568-6, MTHU004940
English Ferritin, Ferritins, ferritin (medication), hematinics ferritin, ferritin, Ferritins [Chemical/Ingredient], ferritins, Ferritin (substance)
Portuguese Ferritinas
Spanish Ferritinas, ferritina (sustancia), ferritina
Italian Ferritine, Ferritina
French Ferritine, Ferritines
Swedish Ferritiner
Czech ferritin, ferritiny
Finnish Ferritiinit
Japanese フェリチン
Croatian FERITIN
Polish Ferrytyna, Ferrytyny
German Ferritin
Derived from the NIH UMLS (Unified Medical Language System)

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