Hematology and Oncology Book



Partial Thromboplastin Time

Aka: Partial Thromboplastin Time, PTT
  1. See Also
    1. Prothrombin Time
    2. Thrombin Time
    3. Whole Blood Clotting Time
    4. Clotting Pathway
    5. Intrinsic Clotting Pathway
    6. Extrinsic Clotting Pathway
    7. Common Clotting Pathway
    8. Bleeding Disorder
  2. Background
    1. Evaluates Intrinsic Clotting Pathway integrity
    2. Plasma collected in a tube containing citrate, which binds Calcium and prevents initial clotting
    3. Calcium is added back to plasma, and time to clotting is measured
  3. Labs: Normal
    1. Range: 25-41 sec
  4. Causes: Increased
    1. Heparin
    2. Warfarin (Coumadin)
    3. Thrombolytics
    4. Clotting Factor deficiency
      1. Factor I Deficiency
      2. Factor II Deficiency
      3. Factor V Deficiency
      4. Factor VIII Deficiency (Hemophilia A)
      5. Factor IX Deficiency (Hemophilia B)
      6. Factor X Deficiency
      7. Factor XI Deficiency
      8. Factor XII Deficiency
    5. Liver disease
    6. Vitamin K Deficiency
    7. Disseminated Intravascular Coagulation (DIC)
    8. Circulating Anticoagulants or specific factor inhibitor
      1. Penicillin reaction
      2. Rheumatoid Factor

Activated Partial Thromboplastin Time measurement (C0030605)

Definition (NCI_CDISC) A measurement of the length of time that it takes for clotting to occur when reagents are added to a plasma specimen. The test is partial due to the absence of tissue factor (Factor III) from the reaction mixture.
Definition (NCI) This is a measurement of the intrinsic pathway of coagulation. Significant deficiency in factors II, V, VIII, IX, X, XI, XII or anticoagulants will prolong PTT. (BioTech Life Science Dictionary)
Definition (MSH) The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of BLOOD COAGULATION. It is used as a screening test and to monitor HEPARIN therapy.
Concepts Laboratory Procedure (T059)
MSH D010314
SnomedCT 400970000, 142980008, 42525009
CPT 1011869
English partial thromboplastin time: PTT, Activated Partial Thromboplastin Time, Partial Thromboplastin Time, Thromboplastin Time, Partial, Activated partial thromboplastin time, partial thromboplastin time (PTT) (lab test), partial thromboplastin time (PTT), PTT, activated PTT, activated partial thromboplastin time (aPTT), activated partial thromboplastin time, activated partial thromboplastin time (aPTT) (lab test), partial thromboplastin time, Activated Partial Thromboplastin Time (APTT) test, aptt, activated ptt, Partial thromboplastin time activated, Activated partial thromboplastin time (procedure), Partial thromboplastin time activated (procedure), Thromboplastin time, partial (PTT), Plasma Thromboplastin Test, APTT, Partial thromboplastin time, activated, PTT, activated, PTT assay, APTT - Activated partial thromboplastin time, PTT - Partial thromboplastin time, Partial thromboplastin time, activated (procedure), Activated Partial Thromboplastin Time measurement, aPTT
Dutch APTT, geactiveerde partiële tromboplastinetijd, Tromboplastinetijd, geactiveerde partiële, Tromboplastinetijd, partiële
French TTPA, TPP (Temps de Thromboplastine Partielle), Temps de thromboplastine partielle, Temps partiel de thromboplastine, Temps partiel de thromboplastine activée, Temps de thromboplastine partielle activée, TPT (Temps Partiel de Thromboplastine), Temps de céphaline activée
German APTT, aktivierte partielle Thromboplastinzeit, Aktivierte partielle Thromboplastinzeit, Partielle Thromboplastinzeit, Thromboplastinzeit, partielle
Italian APTT, Tempo di tromboplastina parziale attivata, Tempo di tromboplastina parziale
Spanish TTPA, activación de tiempo parcial de tromboplastina (procedimiento), activación de tiempo parcial de tromboplastina, PTT, activado, tiempo de tromboplastina parcial, activada (procedimiento), tiempo de tromboplastina parcial, activada, Tiempo de tromboplastina parcial activada, Tiempo de Tromboplastina Parcial Activada, Tiempo de Tromboplastina Parcial
Japanese APTT, カッセイカブブントロンボプラスチンジカン, APTT, セファリン-カオリン凝固時間, トロンボプラスチン時間-部分, 活性化部分トロンボプラスチン時間, 部分トロンボプラスチン時間, カオリン-セファリン凝固時間
Swedish Partiell tromboplastintid
Czech parciální tromboplastinový čas, Aktivovaný parciální tromboplastinový čas, APTT, aktivovaný parciální tromboplastinový čas, aPTT
Finnish APTT
Polish Czas tromboplastyny częściowej, Czas krzepnięcia kaolinowo-kefalinowy, PTT, Czas kefalinowy osocza
Hungarian Aktivált parciális thromboplastin idõ, APTT
Norwegian Partiell tromboplastintid, Tromboplastintid, Tromboplastintid, partiell
Portuguese Tempo parcial de tromboplastina activada, Tempo de Tromboplastina Parcial Ativada, Tempo de Tromboplastina Parcial
Derived from the NIH UMLS (Unified Medical Language System)

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