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Partial Thromboplastin Time
Aka: Partial Thromboplastin Time, PTT- See Also
- Background
- Evaluates Intrinsic Clotting Pathway integrity
- Plasma collected in a tube containing citrate, which binds Calcium and prevents initial clotting
- Calcium is added back to plasma, and time to clotting is measured
- Labs: Normal
- Range: 25-41 sec
- Causes: Increased
- Heparin
- Warfarin (Coumadin)
- Thrombolytics
- Clotting Factor deficiency
- Factor I Deficiency
- Factor II Deficiency
- Factor V Deficiency
- Factor VIII Deficiency (Hemophilia A)
- Factor IX Deficiency (Hemophilia B)
- Factor X Deficiency
- Factor XI Deficiency
- Factor XII Deficiency
- Liver disease
- Vitamin K Deficiency
- Disseminated Intravascular Coagulation (DIC)
- Circulating Anticoagulants or specific factor inhibitor
- Penicillin reaction
- Rheumatoid Factor
Activated Partial Thromboplastin Time measurement (C0030605) |
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Definition (NCI_CDISC) | A measurement of the length of time that it takes for clotting to occur when reagents are added to a plasma specimen. The test is partial due to the absence of tissue factor (Factor III) from the reaction mixture. |
Definition (NCI) | This is a measurement of the intrinsic pathway of coagulation. Significant deficiency in factors II, V, VIII, IX, X, XI, XII or anticoagulants will prolong PTT. (BioTech Life Science Dictionary) |
Definition (MSH) | The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of BLOOD COAGULATION. It is used as a screening test and to monitor HEPARIN therapy. |
Concepts | Laboratory Procedure (T059) |
MSH | D010314 |
SnomedCT | 400970000, 142980008, 42525009 |
CPT | 1011869 |
English | partial thromboplastin time: PTT, Activated Partial Thromboplastin Time, Partial Thromboplastin Time, Thromboplastin Time, Partial, Activated partial thromboplastin time, partial thromboplastin time (PTT) (lab test), partial thromboplastin time (PTT), PTT, activated PTT, activated partial thromboplastin time (aPTT), activated partial thromboplastin time, activated partial thromboplastin time (aPTT) (lab test), partial thromboplastin time, Activated Partial Thromboplastin Time (APTT) test, aptt, activated ptt, Partial thromboplastin time activated, Activated partial thromboplastin time (procedure), Partial thromboplastin time activated (procedure), Thromboplastin time, partial (PTT), Plasma Thromboplastin Test, APTT, Partial thromboplastin time, activated, PTT, activated, PTT assay, APTT - Activated partial thromboplastin time, PTT - Partial thromboplastin time, Partial thromboplastin time, activated (procedure), Activated Partial Thromboplastin Time measurement, aPTT |
Dutch | APTT, geactiveerde partiële tromboplastinetijd, Tromboplastinetijd, geactiveerde partiële, Tromboplastinetijd, partiële |
French | TTPA, TPP (Temps de Thromboplastine Partielle), Temps de thromboplastine partielle, Temps partiel de thromboplastine, Temps partiel de thromboplastine activée, Temps de thromboplastine partielle activée, TPT (Temps Partiel de Thromboplastine), Temps de céphaline activée |
German | APTT, aktivierte partielle Thromboplastinzeit, Aktivierte partielle Thromboplastinzeit, Partielle Thromboplastinzeit, Thromboplastinzeit, partielle |
Italian | APTT, Tempo di tromboplastina parziale attivata, Tempo di tromboplastina parziale |
Spanish | TTPA, activación de tiempo parcial de tromboplastina (procedimiento), activación de tiempo parcial de tromboplastina, PTT, activado, tiempo de tromboplastina parcial, activada (procedimiento), tiempo de tromboplastina parcial, activada, Tiempo de tromboplastina parcial activada, Tiempo de Tromboplastina Parcial Activada, Tiempo de Tromboplastina Parcial |
Japanese | APTT, カッセイカブブントロンボプラスチンジカン, APTT, セファリン-カオリン凝固時間, トロンボプラスチン時間-部分, 活性化部分トロンボプラスチン時間, 部分トロンボプラスチン時間, カオリン-セファリン凝固時間 |
Swedish | Partiell tromboplastintid |
Czech | parciální tromboplastinový čas, Aktivovaný parciální tromboplastinový čas, APTT, aktivovaný parciální tromboplastinový čas, aPTT |
Finnish | APTT |
Russian | KEFALIN-KAOLINOVOGO SVERTYVANIIA VREMIA, KAOLIN-KEFALINOVOGO SVERTYVANIIA VREMIA, TROMBOPLASTINOVOE VREMIA CHASTICHNOE, TROMBOPLASTINOVOE VREMIA PARTSIAL'NOE, КАОЛИН-КЕФАЛИНОВОГО СВЕРТЫВАНИЯ ВРЕМЯ, КЕФАЛИН-КАОЛИНОВОГО СВЕРТЫВАНИЯ ВРЕМЯ, ТРОМБОПЛАСТИНОВОЕ ВРЕМЯ ПАРЦИАЛЬНОЕ, ТРОМБОПЛАСТИНОВОЕ ВРЕМЯ ЧАСТИЧНОЕ |
Polish | Czas tromboplastyny częściowej, Czas krzepnięcia kaolinowo-kefalinowy, PTT, Czas kefalinowy osocza |
Hungarian | Aktivált parciális thromboplastin idõ, APTT |
Norwegian | Partiell tromboplastintid, Tromboplastintid, Tromboplastintid, partiell |
Portuguese | Tempo parcial de tromboplastina activada, Tempo de Tromboplastina Parcial Ativada, Tempo de Tromboplastina Parcial |
Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
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