Hematology and Oncology Book


Common Clotting Pathway

Aka: Common Clotting Pathway, Common Clotting Cascade
  1. See Also
    1. Clotting Pathway
    2. Intrinsic Clotting Pathway
    3. Extrinsic Clotting Pathway
    4. Common Clotting Pathway
    5. Bleeding Disorder
  2. Physiology: Pathway
    1. Factor Xa
      1. Cofactor: Factor V
      2. Inhibitors
        1. Protein C
        2. Protein S
        3. Medications: Direct Xa Inhibitors
    2. Factor II (Prothrombin) converted to IIa (Thrombin)
      1. Fibrinogen cleaved
        1. Fibrinogen cleaved to Fibrin Monomer
        2. Fibrin Monomer coalesced into Fibrin Polymer
      2. Factor XIII converted to XIIIa
        1. Fibrin polymer cross-linked

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