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Antithrombin III deficiency
Aka: Antithrombin III deficiency- Pathophysiology
- Antithrombin III normally inhibits
- Enhanced by Heparin
- Epidemiology
- Heterozygotes have 25-50% ATIII functional levels
- First episode of thrombosis occurs ages 10-30 years
- Complications
- Labs
- Functional level Antithrombin III
Antithrombin III Deficiency (C0272375) |
|
|---|---|
| Definition (NCI) | A rare disorder characterized by the presence of low levels of antithrombin III which prohibits the formation of blood clots. It may be inherited, usually in an autosomal dominant pattern, or acquired. It may lead to venous thrombosis and pulmonary embolism. |
| Definition (MSH) | An absence or reduced level of Antithrombin III leading to an increased risk for thrombosis. |
| Concepts | Disease or Syndrome (T047) |
| MSH | D020152 |
| ICD10 | D68.59 |
| SnomedCT | 36351005 |
| English | AT def - Antithrombin defi, Antithrombin III Deficiency, ANTITHROMBIN III DEFIC, DEFIC ANTITHROMBIN III, ANTITHROMBIN 3 DEFIC, Antithrombin 3 Deficiencies, Antithrombin 3 Deficiency, Deficiencies, Antithrombin 3, Deficiency, Antithrombin 3, Antithrombin III Deficiencies, Deficiencies, Antithrombin III, Deficiency, Antithrombin III, AT-III deficiency, antithrombin III deficiency, antithrombin III deficiency (diagnosis), Antithombin III deficiency, ANTITHROMBIN III DEFICIENCY, Antithrombin III Deficiency [Disease/Finding], antithrombin 3 deficiency, antithrombin deficiency, antithrombin deficiencies, antithrombin iii deficiency, AT3D, THROMBOPHILIA DUE TO ANTITHROMBIN III DEFICIENCY, THPH7, Antithrombin III deficiency, AT deficiency - Antithrombin deficiency, Antithrombin deficiency, Antithrombin III deficiency (disorder) |
| Japanese | アンチトロンビンＩＩＩ欠乏症, ｱﾝﾁﾄﾛﾝﾋﾞﾝ3ｹﾂﾎﾞｳｼｮｳ, Antithrombin III欠損症, アンチトロンビンIII欠損症, AT3欠損症, アンチトロンビン3欠乏症, アンチトロンビン3欠損症, アンチトロンビンIII欠乏症 |
| Swedish | Antitrombin III-brist |
| Czech | antithrombin III - nedostatek, Deficit antitrombinu III |
| Finnish | Antitrombiini III:n puutos |
| Russian | ANTITROMBINA III NEDOSTATOCHNOST', АНТИТРОМБИНА III НЕДОСТАТОЧНОСТЬ |
| Polish | Niedobór antytrombiny III |
| Hungarian | Antithrombin-III-hiány |
| Norwegian | Antitrombin-III-mangel, Antitrombin III-mangel, Antitrombin-3-mangel, Antitrombin 3-mangel |
| Spanish | deficiencia de antitrombina III (trastorno), deficiencia de antitrombina III, Déficit de antitrombina III, Deficiencia de Antitrombina III |
| Portuguese | Carência de antitrombina III, Deficiência de Antitrombina III |
| Dutch | antitrombine III-deficiëntie, Antitrombine-III-deficiëntie, Deficiëntie, antitrombine-III- |
| French | Déficit en antithrombine III, Déficit en AT III, Déficit en AT3, Déficit en antithrombine 3 |
| German | Antithrombin-III-Mangel |
| Italian | Deficit di antitrombina III |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
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