Human Immunodeficiency Virus Book


  • Renal Manifestations of HIV



Renal Manifestations of HIV

Aka: Renal Manifestations of HIV, HIV related renal complications
  1. See Also
    1. HIV Nephropathy
    2. HIV Complications
  2. Associated Conditions: Renal dysfunction
    1. HIV Nephropathy (AIDS associated Nephropathy)
    2. Fluid and Electrolyte abnormalities
      1. SIADH and Hyponatremia common due to occult infection
    3. Drug induced Renal toxicity
      1. See Nephrotoxic Drug
      2. Amphotericin B
      3. Foscarnet
      4. Pentamidine
      5. Bactrim
      6. NSAIDs
      7. Tenofovir Disoproxil fumarate (TDF)
        1. Causes proximal tubule dysfunction (e.g. Hypophosphatemia) and decreased Renal Function
        2. Avoid if GFR <60 ml/min and discontinue if GFR falls more than 25% or <60 ml/min
        3. May safely use Tenofovir Alafenamide as alternative (less nephrotoxic)
  3. References
    1. Chu (2017) Am Fam Physician 96(3): 161-9 [PubMed]

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