Human Immunodeficiency Virus Book



Aka: Etravirine, Intelence
  1. See Also
    1. Anti-Retroviral Therapy
    2. Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI)
      1. Second generation agent
  2. Indications
    1. Anti-Retroviral Therapy experienced patients
    2. Resistance (especially K103N) to first-generation NNRTI (Efavirenz or Nevirapine)
  3. Class
    1. Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI)
  4. Adverse Effects
    1. See NNRTI for class related adverse effects
    2. Rash (20% of patients)
      1. Stop the agent and do not rechallenge
      2. Higher risk in women (30%) than men (18%)
      3. Risk of serious reactions (1-2%)
        1. Stevens-Johnson Syndrome
        2. Toxic Epidermal Necrolysis
        3. Eythema multiforme
    3. Nausea
    4. Peripheral Neuropathy
    5. Hypertension
    6. Hepatotoxicity
    7. Hyperlipidemia
  5. Monitoring
    1. Liver Function Tests
    2. Lipid profile
  6. References
    1. (2008) Med Lett Drugs Ther 50(1288): 47-8 [PubMed]
    2. (1998) Med Lett Drugs Ther 40(1041):115 [PubMed]
    3. (2009) Treat Guidel Med Lett 7(78): 11-22 [PubMed]
Medication Costs
intelence (on 1/14/2017 at Medicaid.Gov Pharmacy Drug pricing)
INTELENCE 100 MG TABLET $9.37 each
INTELENCE 200 MG TABLET $18.94 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

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