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Provera
Aka: Provera, Medroxyprogesterone- Dosing
- Amenorrhea
- Sequential: 5 to 10 mg qd for 5-10 days
- Continuous: 2.5 mg qd
- Dysfunctional Uterine Bleeding (DUB)
- Sequential: 5-10 mg qd for 5-10 days, start on Day 16
- Postmenopausal Estrogen Replacement (with Premarin)
- Sequential: 2.5 to 5 mg PO qd for last 10 cycle days
- Continuous: 5 to 10 mg qd
- Amenorrhea
- Adverse effects
- Major Depression
- Breakthrough bleeding
- Increasing dose to 20-30 mg qd may reduce bleeding
- However may have increased risk
- Long term lipid and cardiovascular effects?
- Increasing dose to 20-30 mg qd may reduce bleeding
| Medication Costs | ||
|---|---|---|
| Medroxyprogesterone Acetate (on 6/18/2017 at Walmart.com) | ||
| Medroxyprogesterone Acetate 10mg | #10 tablets for $4.00 | $0.40 each |
| Medroxyprogesterone Acetate 10mg | #30 tablets for $10.00 | $0.33 each |
| Medroxyprogesterone Acetate 2.5mg | #30 tablets for $4.00 | $0.13 each |
| Medroxyprogesterone Acetate 2.5mg | #90 tablets for $10.00 | $0.11 each |
| Medroxyprogesterone Acetate 5mg | #30 tablets for $4.00 | $0.13 each |
| Medroxyprogesterone Acetate 5mg | #90 tablets for $10.00 | $0.11 each |
| medroxyprogesterone (on 5/17/2017 at Medicaid.Gov Pharmacy Drug pricing) | ||
| MEDROXYPROGESTERONE 10 MG TAB | Generic | $0.15 each |
| MEDROXYPROGESTERONE 150 MG/ML | Generic | $69.86 per ml |
| MEDROXYPROGESTERONE 2.5 MG TAB | Generic | $0.13 each |
| MEDROXYPROGESTERONE 5 MG TAB | Generic | $0.13 each |
| FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. | ||
Medroxyprogesterone (C0025147) |
|
|---|---|
| Definition (NCI) | A synthetic derivative of progesterone administered as an acetate salt (medroxyprogesterone acetate) with antiestrogenic activity. As a do all progestins, medroxyprogesterone binds to and activates nuclear receptors which subsequently bind to and activate target genes for transcription. As an antiestrogen, this agent may inhibit the growth-stimulating effects of estrogen on estrogen-sensitive tumor cells. (NCI04) |
| Definition (NCI_NCI-GLOSS) | A hormonal anticancer drug that is also used in cancer prevention. It belongs to the family of drugs called progestins. |
| Definition (MSH) | (6 alpha)-17-Hydroxy-6-methylpregn-4-ene-3,20-dione. A synthetic progestational hormone used in veterinary practice as an estrus regulator. |
| Definition (CSP) | synthetic progestin derived from 17-hydroxyprogesterone; a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been used to treat breast and endometrial neoplasms. |
| Definition (PDQ) | A synthetic derivative of progesterone administered as an acetate salt (medroxyprogesterone acetate) with antiestrogenic activity. As a do all progestins, medroxyprogesterone binds to and activates nuclear receptors which subsequently bind to and activate target genes for transcription. As an antiestrogen, this agent may inhibit the growth-stimulating effects of estrogen on estrogen-sensitive tumor cells. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39813&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39813&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C629" NCI Thesaurus) |
| Concepts | Pharmacologic Substance (T121) , Hormone (T125) , Steroid (T110) |
| MSH | D008525 |
| SnomedCT | 36621009, 126113007, 27707001 |
| English | 17 alpha-Hydroxy-6 alpha-Methylprogesterone, Methylhydroxyprogesterone, 17 alpha Hydroxy 6 alpha Methylprogesterone, Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6alpha)-, 17Alpha-hydroxy-6alpha-methylprogesterone, 6Alpha-methyl-17alpha-hydroxyprogesterone, 6Alpha-methyl-4-pregnen-17alpha-ol-3,20-dione, (6Alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione, Medroxyprogesterone [Chemical/Ingredient], medroxyPROGESTERone, MEDROXYPROGESTERONE, medroxyprogesterone, Medroxyprogesterone preparation, Medroxyprogesterone (substance), Medroxyprogesterone preparation (product), MPA, Medroxyprogesterone acetate preparation (substance), Medroxyprogesterone preparation (substance), Medroxyprogesterone |
| Swedish | Medroxiprogesteron |
| Czech | medroxyprogesteron |
| Finnish | Medroksiprogesteroni |
| Russian | MEDROKSIPROGESTERON, METIPREGNON, METILGIDROKSIPROGESTERON, МЕДРОКСИПРОГЕСТЕРОН, МЕТИЛГИДРОКСИПРОГЕСТЕРОН, МЕТИПРЕГНОН |
| Japanese | メチルヒドロキシプロゲステロン, メドロキシプロゲステロン |
| Spanish | preparado con medroxiprogesterona (producto), medroxiprogesterona (producto), preparado con medroxiprogesterona, medroxiprogesterona (sustancia), medroxiprogesterona, preparado de medroxiprogesterona (producto), preparado de medroxiprogesterona (sustancia), preparado de medroxiprogesterona, Medroxiprogesterona, Metilhidroxiprogesterona |
| Croatian | MEDROKSIPROGESTERON |
| Polish | Medroksyprogesteron |
| French | Médroxyprogestérone |
| German | Medroxyprogesteron, Methylhydroxyprogesteron |
| Italian | Medrossiprogesterone |
| Portuguese | Medroxiprogesterona, Metilidroxiprogesterona |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Provera (C0699702) |
|
|---|---|
| Definition (CHV) | brand name of a synthetic female sex hormone |
| Definition (CHV) | brand name of a synthetic female sex hormone |
| Concepts | Pharmacologic Substance (T121) , Steroid (T110) |
| MSH | D017258 |
| English | provera, provera [brand name], Provera |
| Czech | Provera |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
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