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Progestin Endometrial Activity
Aka: Progestin Endometrial Activity, Endometrial Activity
- See Also
- Oral Contraceptive
- Progestin
-
General
- Ability to prevent spotting or breakthrough bleeding
- Dependent on Estrogen-Progestin ratio
- Bleeding may be due to:
- Estrogen insufficiency
- Progesterone insufficiency
-
Progestins with least potent Endometrial Activity
- Amount to suppress bleeding for 20 days in 50% women
- Gestodene (12.6)
- Desogestrel (8.7)
- Levonorgestrel (5.1)
- dl-Norgestrel (2.6)
-
Progestins with most Endometrial Activity
- Amount to suppress bleeding for 20 days in 50% women
- Norethynodrel (0): Low limit reference
- Norethindrone Acetate (0.4)
- Ethynodiol Diacetate (0.4)
- Norethindrone (1.0)
-
Oral Contraceptives with least Endometrial Activity
- Least suppression of bleeding
- Progestin-Only (Mini-Pill)
- Demulen 1/35
- Loestrin
- Tri-Norinyl
-
Oral Contraceptives with most Endometrial Activity
- Greatest suppression of bleeding
- Ovral
- Lo-Ovral
- Ortho Novum
- Ovcon
- Norlestrin
- Demulen 50
- References
- Cerel-Suhl (1999) Am Fam Physician 60(7):2073 [PubMed]
- Speroff (1993) Obstet Gynecol 81:1034-47 [PubMed]
- Dickey (1998) Managing Contraceptive Pill Patients