Gynecology Book



Aka: Ortho-Cyclen, OrthoCyclen, Ortho Cyclen, Cilest, MonoNessa, Sprintec
  1. See Also
    1. Oral Contraceptive
    2. Oral Contraceptive Drug Interaction
    3. Oral Contraceptive Selection
    4. Oral Contraceptive Side Effect Management
    5. Oral Contraceptive-Related Uterine Bleeding Management
  2. Preparations: Norgestimate 250 mcg and Ethinyl Estradiol 35 mcg
    1. Ortho-Cyclen, MonoNessa or Sprintec
    2. Cilest (UK)
  3. Components
    1. Norgestimate 25 mcg
    2. Ethinyl Estradiol 35 mcg
  4. Effect
    1. Relative Progestational Activity: 0.3 (low)
    2. Estrogenic Activity: 35 (moderate)
    3. Androgenic Activity: 0.18 (low)
  5. Pill associated problems (Same as Ortho Tri-Cyclen)
    1. Indications to switch to Modicon
      1. Acne Vulgaris (lower androgen)
      2. Increased Appetite (lower Progestin)
      3. Break-through bleed days 1-9 (more Estrogen)
      4. Break-through bleed all of month (more Estrogen)
      5. Major Depression provoked (lower Progestin)
      6. Menses too light (more Estrogen, less Progestin)
    2. Indications to switch to Demulen 1/35
      1. Breast Tenderness or engorgement (lower Estrogen)
      2. Break-through bleed days 10-21 (more Progestin)
      3. Headaches (lower Estrogen)
      4. Heavy Menses (more Progestin or less Estrogen)
      5. Dysmenorrhea or Menstrual Cramps (more Progestin)
      6. Moodiness (less Estrogen or more Progestin)
      7. Weight gain (less Estrogen or more Progestin)
    3. Indications to switch to Lo/Ovral
      1. Libido decreased (more androgen)
  6. References
    1. Cerel-Suhl (1999) Am Fam Physician 60(7):2073 [PubMed]
    2. Speroff (1993) Obstet Gynecol 81:1034-47 [PubMed]
    3. Dickey (1998) Managing Contraceptive Pill Patients
Medication Costs
Sprintec (on 6/18/2017 at
Sprintec #28 tablets for $9.00 $0.32 each
ortho-cyclen (on 2/22/2017 at Medicaid.Gov Pharmacy Drug pricing)
ORTHO-CYCLEN 28 TABLET Generic $0.29 each
mononessa (on 5/17/2017 at Medicaid.Gov Pharmacy Drug pricing)
MONONESSA 28 TABLET Generic $0.29 each
sprintec (on 5/17/2017 at Medicaid.Gov Pharmacy Drug pricing)
SPRINTEC 28 DAY TABLET Generic $0.29 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

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