Gynecology Book



Aka: Lo/Ovral, Lo-Ovral, LoOvral, Cryselle, Low-Ogestrel
  1. See Also
    1. Oral Contraceptive
    2. Oral Contraceptive Drug Interaction
    3. Oral Contraceptive Selection
    4. Oral Contraceptive Side Effect Management
    5. Oral Contraceptive-Related Uterine Bleeding Management
  2. Preparations (Norgestrel 300 mcg / Ethinyl Estradiol 30 mcg)
    1. Lo-Ovral
    2. Cryselle
    3. Low-Ogestrel
  3. Components
    1. Norgestrel 300 mcg (see preparation above)
    2. Ethinyl Estradiol 30 ug
  4. Effects
    1. Relative Progestational Activity: 0.8 (moderate)
    2. Estrogenic Activity: 25 (moderate)
    3. Androgenic Activity: 0.46 (high)
  5. Adverse Effects: Pill associated problems
    1. Indications to switch to Ortho Novum 777
      1. Acne Vulgaris (lower androgen)
    2. Indications to switch to Ortho Cyclen
      1. Increased Appetite (lower Progestin)
      2. Major Depression provoked (lower Progestin)
    3. Indications to switch to Loestrin 1.5/30
      1. Breast Tenderness or engorgement (lower Estrogen)
      2. Headaches (lower Estrogen)
      3. Moodiness (less Estrogen or more Progestin)
      4. Weight gain (less Estrogen or more Progestin)
      5. Libido decreased (more androgen)
    4. Indications to switch to Ortho Novum 1/35
      1. Break-through bleed days 1-9 (more Estrogen)
      2. Break-through bleed all of month (more Estrogen)
      3. Menses too light (more Estrogen, less Progestin)
    5. Indications to switch to Demulen 1/35
      1. Break-through bleed days 10-21 (more Progestin)
      2. Heavy Menses (more Progestin or less Estrogen)
      3. Dysmenorrhea or Menstrual Cramps (more Progestin)
  6. References
    1. Cerel-Suhl (1999) Am Fam Physician 60(7):2073 [PubMed]
    2. Speroff (1993) Obstet Gynecol 81:1034-47 [PubMed]
    3. Dickey (1998) Managing Contraceptive Pill Patients
Medication Costs
cryselle (on 5/17/2017 at Medicaid.Gov Pharmacy Drug pricing)
CRYSELLE-28 TABLET Generic $0.47 each
low-ogestrel (on 5/17/2017 at Medicaid.Gov Pharmacy Drug pricing)
LOW-OGESTREL-28 TABLET Generic $0.47 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

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