Geriatric Medicine Book



Aka: Frailty, Sarcopenia
  1. Definitions
    1. Frailty
      1. Physiologic decline with advancing age, with associated increased risk of adverse health outcomes
      2. Findings include slow gait, Unintentional Weight Loss, sedentary
    2. Sarcopenia
      1. Catabolic age-related loss of muscle mass and strength
      2. Findings include reduced grip strength, gait speed and muscle mass
  2. Diagnosis: Frailty (Three or more of the following criteria)
    1. Unintentional Weight Loss of at least 10 lb (4.5 kg) in the last year
    2. Self-reported exhaustion
    3. Weakness (decreased grip strength)
    4. Slow walking speed
    5. Low Physical Activity
  3. Management
    1. Exercise program
      1. See Exercise in the Elderly
    2. Vitamin Supplementation (controversial)
      1. Vitamin D Supplementation
      2. Protein Supplementation
  4. References
    1. Fried (2001) J Gerontol A Biol Sci Med Sci 56(3): M146-56 +PMID:11253156 [PubMed]

Frailty (C0424594)

Concepts Finding (T033)
ICD10 R54
SnomedCT 248279007
Dutch geringe belastbaarheid
French Fragilité
German Gebrechlichkeit
Italian Fragilità
Portuguese Fragilidade
Spanish Estado debilitado, debilidad (hallazgo), debilidad
Japanese 虚弱, キョジャク
Czech Křehkost, slabost
English frailty (diagnosis), frailty, Frailty (finding), Frailty
Hungarian Törékenység
Derived from the NIH UMLS (Unified Medical Language System)

Sarcopenia (C0872084)

Definition (MSH) Progressive decline in muscle mass due to aging which results in decreased functional capacity of muscles.
Definition (CSP) loss of skeletal muscle mass, quality and strength; may be associated with aging.
Concepts Finding (T033)
MSH D055948
Japanese 筋肉減少症, キンニクゲンショウショウ
Czech Sarkopenie, sarkopenie
English Sarcopenia, Sarcopenias, Sarcopenia [Disease/Finding], sarcopenia
French Sarcopénie, Sarcoporose
German Muskelschwund, Sarkopenie
Italian Sarcopenia
Portuguese Sarcopenia
Spanish Sarcopenia
Swedish Sarkopeni
Polish Sarkopenia
Hungarian Sarcopenia
Norwegian Sarkopeni
Dutch sarcopenie
Derived from the NIH UMLS (Unified Medical Language System)

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