Gastroenterology Book



Aka: Laxative
  1. See Also
    1. Constipation
    2. Functional Constipation
    3. Pediatric Constipation
  2. Types: Laxative Types
    1. Bulk Laxative (Fiber Supplementation, Preferred agents)
      1. Preferred agents (effective with few adverse effects)
      2. Psyllium (e.g. Metamucil)
      3. Methylcellulose (e.g. Citrucel)
      4. Calcium Polycarbophil (Fibercon)
      5. Dietary Fiber
    2. Osmotic Laxative (Preferred agents)
      1. Poorly absorbed saccharides (Lactulose, Sorbitol)
      2. Magensium Laxatives (Milk of Magnesia)
      3. Sodium bisphosphate (Fleets Phospho-Soda)
      4. Polyethylene glycol lavage solution (GoLytely)
    3. Emollient Laxative (Stool Softener)
      1. DocusateSodium (Colace) - questionable efficacy
      2. Glycerin
      3. Mineral Oil (not recommended)
        1. Aspiration risk
        2. Depletes fat soluble Vitamins
    4. Stimulant Laxative (Risk of Laxative abuse)
      1. Other Laxative types are preferred over these
      2. Anthraquinone Laxative
        1. Cascara sagrada Extract (Casanthranol)
        2. Senna Extract (Senokot)
      3. Diphenylmethane Laxative
        1. Bisacodyl (Dulcolax)
        2. Phenolphthalein (OTC, Correctol, Ex-Lax)
    5. Combination Agents
      1. Peri-Colace contains Cascara and Docusate
      2. Senekot-S contains senna and Docusate
    6. Enemas and suppositories
      1. Never use hot water, soap, or Hydrogen Peroxide enema
      2. Tap water enema or saline enema (safest)
      3. Sodium Bisphosphate enema (Fleet Enema)
      4. Pink Lady Enema (1/2 Fleet Enema, 100 ml Docusate, 60 ml Mineral Oil, 60 ml Magnesium Citrate)
      5. Mineral Oil enema
      6. Glycerine suppository
      7. Bisacodyl suppository (dulcolax suppository)
    7. Prokinetic agents
      1. Tegaserod (Zelnorm)
        1. Indicated only in IBS for Constipation in women
Medication Costs
laxative (on 12/21/2016 at Medicaid.Gov Pharmacy Drug pricing)
LAXATIVE 25 MG PILL Generic OTC $0.10 each
LAXATIVE 5 MG TABLET Generic OTC $0.05 each
LAXATIVE EC 5 MG TABLET Generic OTC $0.02 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

Laxatives (C0282090)

Definition (CHV) a drug used to treat constipation by increasing bowel movement
Definition (CHV) a drug used to treat constipation by increasing bowel movement
Definition (NCI) Synthetic compounds or mixtures administered orally or rectally with laxative activity. A laxative preparation is used to promote bowel movement to treat constipation or to clean the colon for rectal and bowel examinations. There are different types of laxatives that differ in mechanism of action and potency, including the bulk-producing agents, stool softeners, lubricants, hydrating agents, stimulants, saline laxatives and hyperosmotic agents.
Definition (NCI_NCI-GLOSS) A substance that promotes bowel movements.
Definition (CSP) agent that acts to promote evacuation of the bowel; a cathartic or purgative.
Definition (MSH) Agents that produce a soft formed stool, and relax and loosen the bowels, typically used over a protracted period, to relieve CONSTIPATION.
Concepts Pharmacologic Substance (T121)
MSH D054368
SnomedCT 317640001, 372800002, 61621000
LNC LP18988-3, MTHU007218
English Other laxatives, LAXATIVES,OTHER, LAXATIVES, Laxatives, laxatives (medication), laxatives, GI preparations laxatives, Laxative Preparation, [GA209] LAXATIVES,OTHER, [GA200] LAXATIVES, laxative, Other laxatives (product), Laxative, Laxative (product), Laxative (substance), Laxative, NOS, Other laxatives (substance), Mild cathartic
Portuguese Laxantes, Laxativos
Spanish Laxativos, otros laxantes, otros laxantes (producto), Laxantes, laxante (producto), laxante (sustancia), laxante
Finnish Ulostuslääkkeet
French Agents laxatifs, Médicaments laxatifs, Laxatifs
German Laxantien
Italian Lassativi
Czech projímadla, laxancia, laxativa
Swedish Avföringsmedel
Polish Leki przeczyszczające
Japanese 緩下剤, 緩下薬
Derived from the NIH UMLS (Unified Medical Language System)

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