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Lactulose
Aka: Lactulose- See Also
- Mechanism
- Converts Ammonia to unabsorbed Ammonium
- Produces Diarrhea
- Alters bowel flora
- Indications
- Advantages
- Poorly absorbed (may be used in Renal Failure)
- Disadvantages: Constipation
- Not as effective or well tolerated as Miralax
- Dosages
- Constipation
- Lactulose (Chronulac)
- Lactitol
- As effective as Lactulose with less pain and Flatus
- Pitzalis (1995) Pediatr Med Chir 17(3):223-6 [PubMed]
- Hepatic Encephalopathy
- Initial: 30-50 ml PO qh until Diarrhea
- Next: 15-30 ml PO tid-qid prn 2-3 stools/day
- Hepatic Coma
- Lactulose 300 ml in 700 ml water retention enema
- Constipation