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Helicobacter pylori Invasive Testing
Aka: Helicobacter pylori Invasive Testing, H. pylori culture, Endoscopic Biopsy for H. pylori, Rapid Urease Test, CLO Test
- See Also
- Helicobacter pylori Noninvasive Testing
- Indications
- Dyspepsia evaluation
- Tests
- Gastric Biopsy with Steiner's Stain
- Test Sensitivity: 95%
- Test Specificity: 99-100%
- Rapid Urease Test (e.g. CLO Test)
- Test Sensitivity: 93-97%
- Test Specificity: >95%
- H. pylori culture
- Test Sensitivity: 70-80%
- Test Specificity: 100%
- Advantages
- Gold standard for H. pylori diagnosis
- Confirms cure for H. pylori
- Disadvantages
- Requires endoscopic biopsy
- Sensitivity altered for histology and urease activity
- Proton Pump Inhibitors
- Antibiotics
- Bismuth
- References
- Meurer (2002) Am Fam Physician 65(7):1327-39 [PubMed]
- Snyder (1999) Can J Gastroenterol 13:585-9 [PubMed]