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Gamma glutamyl transferase
Aka: Gamma glutamyl transferase, GGT- See Also
- Pathophysiology
- Membrane bound hepatic cell marker
- Suggests cholestasis
- Most sensitive, but least specific of all LFTs
- Normal: 0-30 U/L
- Increased (Elevation 3 times normal is significant)
- Chronic Alcoholic Hepatitis or other liver disease
- Liver neoplasm or metastases
- Nephrotic Syndrome
- Cholestasis
- Pancreatic Carcinoma
- Congestive Heart Failure (CHF)
- Sepsis
- Systemic Lupus Erythematosus (SLE)
- Medications
Gamma-glutamyl transferase (C0017040) |
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|---|---|
| Definition (NCI) | GGT participates in the transfer of amino acids across the cellular membrane and in glutathione metabolism. High concentrations are found in the liver, bile ducts, and the kidney. A test that measures the amount of GGT in the blood is used to detect diseases of the liver, bile ducts, and kidney; and to differentiate liver or bile duct (hepatobiliary) disorders from bone disease.(from http://health.allrefer.com) |
| Definition (MSH) | An enzyme, sometimes called GGT, with a key role in the synthesis and degradation of GLUTATHIONE; (GSH, a tripeptide that protects cells from many toxins). It catalyzes the transfer of the gamma-glutamyl moiety to an acceptor amino acid. |
| Concepts | Amino Acid, Peptide, or Protein (T116) , Enzyme (T126) |
| MSH | D005723 |
| SnomedCT | 60153001 |
| LNC | LP15590-0, MTHU001941 |
| English | GGTP, Gamma-Glutamyl transferase, gamma Glutamyl Transpeptidase, Glutamyl Transpeptidase, Transpeptidase, Glutamyl, Transpeptidase, gamma-Glutamyl, gamma Glutamyltransferase, gamma-Glutamyl Transpeptidase, gamma-Glutamyltransferase, (5-L-Glutamyl)-peptide:amino-acid 5-glutamyltransferase, GGT, glutamyl transpeptidase, gamma glutamyltranspeptidase, GGT - Gamma-glutamyl transf, Gamma-glutamyl transferase, gamma-Glutamyltransferase [Chemical/Ingredient], gamma glutamyl transferase, gamma glutamyl transpeptidase, ggtp, gamma glutamyltransferase, gamma-glutamyl transferase, gamma-glutamyl transpeptidase, gamma-glutamyltransferase, gammaglutamyltransferase, EC 2.3.2.2, Gamma glutamyl transferase, Gamma-Glutamyltransferase, Glutamyl transpeptidase, gamma GTP, GGT - Gamma-glutamyl transferase, Gamma-glutamyl transpeptidase, gamma-Glutamyltransferase (substance), Gamma-GT, Gamma-Glutamyl Transpeptidase |
| Czech | gama-glutamyltransferasa |
| Finnish | Glutamyylitransferaasi |
| Italian | Glutamil transpeptidasi, Gamma-glutamil transpeptidasi, GGTP, Gammaglutamiltransferasi, Gamma-glutamiltransferasi |
| Russian | GLUTAMILTRANSPEPTIDAZA, GAMMA-GLUTAMILTRANSFERAZA, ГАММА-ГЛУТАМИЛТРАНСФЕРАЗА, ГЛУТАМИЛТРАНСПЕПТИДАЗА |
| Japanese | ガンマ-グルタミルトランスフェラーゼ, γ-グルタミルトランスフェラーゼ, γ-グルタミルトランスペプチダーゼ, グルタミルトランスペプチダーゼ, グルタミルペプチド転移酵素 |
| Swedish | Gammaglutamyltransferas |
| Croatian | GAMA-GLUTAMILTRANSFERAZA |
| French | GGT (Gamma-Glutamyl Transpeptidase), gamma-Glutamyltransferase, gamma-GT, Glutamyl transpeptidase |
| Spanish | gammaglutamiltransferasa, gamma-Glutamiltransferasa, gamma - glutamiltransferasa (sustancia), gamma - glutamiltransferasa, glutamil transpeptidasa, GGTP, Glutamil Transpeptidasa |
| Polish | Glutamylotranspeptydaza, Transpeptydaza gamma-glutamylowa, GGTP, Gamma-glutamylotransferaza |
| German | GGTP, Gamma-Glutamyltransferase, Glutamyl-Transpeptidase, Gammaglutamyltransferase |
| Portuguese | GGTP, gama-Glutamiltransferase, gamaglutamiltransferase, Glutamil Transpeptidase |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
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