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Medications with Adverse Ocular Effects
Aka: Medications with Adverse Ocular Effects, Ocular Adverse Effects of Medications
- Causes
- Amiodarone
- Repeat Eye Exam every 6-12 months
- Possible risk of nonarteritic Ischemic Optic Neuropathy
- Colored halos around lights and increased glare
- Antituberculosis Agents (Ethambutol, and to lesser extent Isoniazid)
- Baseline eye specialist exam with periodic follow-up
- Optic Neuritis and Visual Field defects
- Bisphosphonates (e.g. Fosamax)
- Episcleritis, Scleritis and Conjunctivitis
- Glaucoma may be associated with Fosamax
- COX-2 Inhibitors
- Blurred Vision and Conjunctivitis (resolves within 3 days of stopping medication)
- Hydroxychloroquine (Plaquenil)
- Prolonged use in over age 60 should be followed by eye specialist
- Corneal and Retinal deposits (low risk with short-term use)
- Altered color Vision
- Phosphodiesterase Inhibitors (e.g. Viagra)
- Altered color Vision and Blurred Vision
- Photophobia and other ocular pain
- Possible risk of nonarteritic Ischemic Optic Neuropathy
- Tamoxifen
- Consider baseline eye specialist exam with periodic follow-up
- Corneal and Retinal deposits, loss of Vision (1-2% longterm risk)
- References
- Santaella (2007) Drugs 67(1): 75-93 [PubMed]