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Herpes Simplex Keratitis
Aka: Herpes Simplex Keratitis, Herpes Keratitis, Herpetic Keratitis, Herpes Simplex Conjunctivitis, HSV Conjunctivitis, Herpetic Dendrite, Dendritic Keratitis, Dendritic Ulcer- Epidemiology
- Outbreaks in winter and early summer
- Symptoms
- Previous history of Herpes Keratitis
- Coexisting Fever Blister (herpetic rash) on lip or upper face
- Recent Upper Respiratory Infection
- Absent history of Corneal Trauma
- Severe Eye Pain
- Photophobia
- Eye Discharge
- Gritty Sensation in eye
- Signs
- Unilateral inflammation of Conjunctiva and Cornea
- Dendritic Ulcers on Fluorescein staining of Cornea (consider rose bengal strips if available)
- Reduced Corneal sensitivity
- Preauricualar node (anterior to tragus)
- Complications
- Corneal Ulcer and scarring with obscured Vision
- Management
- Urgent Ophthalmology referral
- Consider Hospital admission
- AVOID Topical Steroids
- Topical antivirals
- Ganciclovir 0.15% ophthalmic gel (Zirgan)
- Trifluridine 1% drops (Viroptic)
- Systemic Acyclovir or other antiviral agents
- References
- Williams (2017) Crit Dec Emerg Med 31(2): 3-12
- Pflipsen (2016) Am Fam Physician 93(12): 991-8 [PubMed]
Keratitis, Herpetic (C0019357) |
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Definition (MSHFRE) | Infection de l'épithélium de la cornée due au virus herpès hominis. Elle est caractérisée par de petites vésicules qui peuvent éclater et fusionner pour former un ulcère dendritique. (Dictionary of Visual Science, 3d ed) |
Definition (MSHCZE) | Keratitis dendritica – lat. povrchový zánět rohovky (keratitida) vznikající při infekci virem herpes simplex (herpes corneae). Defekty rohovkového epitelu vytvářejí větvičkové struktury (srov. keratitis punctata superficialis). Typická pro virové postižení rohovky je její hypestezie až anestezie. (cit. Velký lékařský slovník online, 2013 http://lekarske.slovniky.cz/ ) |
Definition (CSP) | herpes of the eye and its adnexa. |
Definition (MSH) | A superficial, epithelial Herpesvirus hominis infection of the cornea, characterized by the presence of small vesicles which may break down and coalesce to form dendritic ulcers (KERATITIS, DENDRITIC). (Dictionary of Visual Science, 3d ed) |
Concepts | Disease or Syndrome (T047) |
MSH | D016849 |
SnomedCT | 186546003, 154335009, 186547007, 283161000009101, 186542001, 9389005 |
English | Herpes Simplex Keratitides, Herpes Simplex Keratitis, Herpes Simplex, Ocular, Herpetic Keratitides, Herpetic Keratitis, Keratitides, Herpes Simplex, Keratitides, Herpetic, Keratitis, Herpes Simplex, Keratitis, Herpetic, Ocular Herpes Simplex, HERPES OCULAR, Ophthalmic herpes simplex NOS, HERPES SIMPLEX KERATITIS, Herpes simplex keratitis (diagnosis), Herpes ocular, Herpes ophthalmic NOS, Keratitis, Herpetic [Disease/Finding], herpes keratitis, eyes herpes, herpes ocular, herpes ophthalmic, ocular simplex herpes, eye herpes, Herpes;eye, Herpes simplex;ophthalmic, hsv keratitis, herpes eye, herpetic keratitis, ocular herpes, ophthalmic herpes, herpes simplex keratitis, corneal herpes, ocular herpes simplex, Ophthalmic herpes simplex NOS (disorder), Corneal herpes, Keratitis herpetic, Herpes simplex ophthalmic, Keratitis due to Herpesvirus, Herpesvirus keratitis, Keratitis due to Herpesvirus (disorder), Herpes simplex ophthalmicus, Herpes ophthalmic, Herpes simplex keratitis, Ophthalmic herpes simplex, Herpetic keratitis, HSV keratitis, Herpes simplex keratitis (disorder), Ophthalmic herpes simplex (disorder), herpes of the eye, ophthalmic herpes simplex |
Italian | Herpes oftalmico, Herpes oftalmico NAS, Herpes oculare, Herpes simplex oculare, Cheratite da herpes simplex, Herpes simplex oftalmico, Herpes della cornea, Cheratite erpetica |
Dutch | herpes oftalmisch NAO, herpes oculair, oftalmische herpes simplex, herpetische keratitis, keratitis herpetisch, herpes-simplex-keratitis, herpes simplex oftalmisch, hoornvliesherpes, herpes oftalmisch, Herpes simplex, oculaire, Herpes-simplexkeratitis, Keratitis herpetica |
French | Herpès ophtalmique SAI, HERPES OCULAIRE, Herpès cornéen, Herpes simplex oculaire, Herpès simplex ophtalmique, Kératite due à Herpes simplex, Herpès ophtalmique, Herpès simplex oculaire, Kératite herpétique, Herpès oculaire |
German | Herpes, okulaer, Herpes des Auges NNB, HERPES AUGE, Hornhautinfektion durch Herpes, Herpes simplex des Auges, Keratitis durch Herpes, Keratitis durch Herpes simplex, Herpes simplex am Auge, herpetische Keratitis, Herpes des Auges, Herpes corneae, Herpes-simplex-Keratitis, Keratitis, Herpes-, Herpes simplex, okulärer |
Portuguese | Herpes oftálmico NE, Herpes ocular, HERPES OCULAR, Herpes da córnea, Queratite de herpes simples, Queratite herpética, Herpes simples oftálmico, Herpes oftálmico, Ceratite Herpética, Ceratite por Herpes Simples, Herpes Simples Ocular |
Spanish | Herpes ocular, Herpes oftálmico NEOM, HERPES OCULAR, Herpes simplex oftálmico, SAI (trastorno), Herpes simplex oftálmico, SAI, Queratitis herpética, Herpes corneal, Queratitis por herpes simplex, Herpes simplex oftálmico, herpes simple oftálmico (trastorno), herpes simple oftálmico, queratitis herpética, queratitis por virus del herpes simple (trastorno), queratitis por virus del herpes simplex, queratitis por virus del herpes simple, Herpes oftálmico, queratitis por Herpes simplex, Herpes Simple Ocular, Queratitis Herpética, Queratitis por Herpes Simple |
Japanese | ヘルペス眼感染NOS, ヘルペス眼感染, 眼ヘルペス, ヘルペスガンカンセンNOS, ガンヘルペス, ヘルペスガンカンセン, 単純ヘルペス-眼部, 角膜炎-単純ヘルペス, ガンブタンジュンヘルペス, カクマクヘルペス, 単純ヘルペス性角膜炎, タンジュンヘルペスセイカクマクエン, ヘルペスセイカクマクエン, ヘルペス性角膜炎, 単純ヘルペス角膜炎, 疱疹性角膜炎, 眼部単純ヘルペス, 角膜ヘルペス, 角膜疱疹, 角膜炎-ヘルペス性, 角膜炎-疱疹性 |
Swedish | Herpeskeratit |
Czech | keratitida herpetická, Oční herpetická infekce, Herpes ophthalmicus, Oční herpetická infekce NOS, Herpes simplex oka, Herpes rohovky, Oční Herpes simplex, Keratitida způsobená herpes simplex virem, Herpetická keratitida |
Finnish | Herpeskeratiitti |
Russian | KERATIT GERPETICHESKII, GERPETICHESKII KERATIT, GERPES PROSTOI GLAZA, ГЕРПЕС ПРОСТОЙ ГЛАЗА, ГЕРПЕТИЧЕСКИЙ КЕРАТИТ, КЕРАТИТ ГЕРПЕТИЧЕСКИЙ |
Croatian | Not Translated[Keratitis, Herpetic] |
Polish | Opryszczka zwykła oka, Zapalenie rogówki opryszczkowe |
Hungarian | Herpes ocularis, Herpes ophthalmicus, herpes ophthalmicus k.m.n., herpes simplex ophthalmicus, keratitis herpetica, Herpes simplex keratitis, herpeses keratitis, Herpes simplex ophthalmicus, Cornealis herpes |
Norwegian | Herpes simplex-keratitt, Okulær herpes simplex, Keratitt, herpetisk, Herpeskeratitt, Herpetisk keratitt |
Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Keratitis, Dendritic (C0022570) |
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Definition (MSHCZE) | Keratitis dendritica – lat. povrchový zánět rohovky (keratitida) vznikající při infekci virem herpes simplex (herpes corneae). Defekty rohovkového epitelu vytvářejí větvičkové struktury (srov. keratitis punctata superficialis). Typická pro virové postižení rohovky je její hypestezie až anestezie. (cit. Velký lékařský slovník online, 2013 http://lekarske.slovniky.cz/ ) |
Definition (MSH) | A form of herpetic keratitis characterized by the formation of small vesicles which break down and coalesce to form recurring dendritic ulcers, characteristically irregular, linear, branching, and ending in knoblike extremities. (Dictionary of Visual Science, 3d ed) |
Concepts | Disease or Syndrome (T047) |
MSH | D007635 |
ICD9 | 054.42 |
SnomedCT | 29943008 |
English | Dendritic Keratitides, Furrow Keratitides, Furrow Keratitis, Keratitides, Dendritic, Keratitides, Furrow, Keratitis, Dendritic, Keratitis, Furrow, Herpes simp.dendritic keratit., keratitis dentritic, dendritic keratitis (diagnosis), dendritic keratitis, epithelial dendritic keratitis was observed, dendritic Herpes simplex keratitis, dendritic Herpes simplex keratitis (diagnosis), dendritic keratitis (physical finding), Keratitis, Dendritic [Disease/Finding], Dendritic keratitis, Herpes simplex dendritic keratitis, HSV dendritic keratitis, Herpes simplex dendritic keratitis (disorder), Dendritic Keratitis |
Swedish | Keratit, dendritisk |
Czech | keratitida dendritická, Keratitis dendritica, keratitis dendritica |
Finnish | Dendriittinen keratiitti |
Russian | KERATIT DREVOVIDNYI, DREVOVIDNYI KERATIT, ДРЕВОВИДНЫЙ КЕРАТИТ, КЕРАТИТ ДРЕВОВИДНЫЙ |
Croatian | KERATITIS, DENDRITIČKI |
Polish | Zapalenie rogówki herpetyczne, Opryszczka rogówki, Zapalenie rogówki drzewiaste |
Japanese | 角膜炎-溝状, 角膜炎-樹枝状, ジュシジョウカクマクエン, 樹枝状角膜潰瘍, 樹枝状角膜炎, 溝状角膜炎 |
Norwegian | Keratitt, dendrittisk, Dendrittisk keratitt, Keratitis dendritica |
Dutch | dendritische keratitis, Furrow-keratitis, Keratitis dendritica, Keratitis, Furrow- |
German | dendritische Keratitis, Furchenkeratitis, Keratitis dendritica, Keratitis, Furchen- |
Hungarian | Dendriticus keratitis |
Portuguese | Queratite dendrítica, Ceratite de Furrow, Ceratite Dendrítica |
Spanish | Queratitis dendrítica, queratitis dendrítica herpética, queratitis dendrítica por virus del herpes simple (trastorno), queratitis dendrítica por virus del herpes simplex, queratitis dendrítica por virus del herpes simple, queratitis dendrítica por Herpes simplex, Queratitis de Furrow, Queratitis Dendrítica |
French | Kératite dendritique |
Italian | Cheratite dendritica |
Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Dendritic ulcer (C0333303) |
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Concepts | Acquired Abnormality (T020) |
SnomedCT | 63280002, 246935009, 155153004, 193764001 |
English | Dendritic ulceration, Herpetic ulceration of cornea, Dendritic ulcer (M-38190), dendritic ulcer, Ulcer;dendritic, dendritic ulcers, Dendritic ulceration (disorder), Dendritic ulcer, Dendritic ulcer (disorder), Dendritic ulcer (morphologic abnormality) |
Czech | Dendritický vřed rohovky |
Dutch | dendritische zweer |
French | Ulcère dendritique |
German | dendritisches Ulkus |
Hungarian | Dendriticus fekély |
Italian | Ulcera dendritica |
Japanese | ジュシジョウカイヨウ, 樹枝状潰瘍 |
Portuguese | Úlcera dendrítica |
Spanish | Úlcera dendrítica, úlcera dendrítica (anomalía morfológica), úlcera dendrítica (trastorno), úlcera dendrítica |
Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
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