Endocrinology Book



Aka: Phentermine, Lonamin, Fastin, Lomaira
  1. See Also
    1. Medications Associated with Weight Gain
    2. Orlistat (Xenical)
    3. Lorcaserin (Belviq)
    4. Phentermine and Topiramate (Qsymia, Qnexa)
    5. Obesity
    6. Obesity in Children
    7. Obesity Evaluation
    8. Obesity Measurement (or Obesity Screening)
    9. Obesity Risk (or Obesity Comorbid Conditions)
    10. Obesity Management
    11. Obesity Medication
    12. Dietary Supplements in Obesity
    13. Exercise in Obesity
    14. Obesity Resources
  2. Mechanism
    1. Stimulates CNS adrenergic system
    2. Reduces food seeking behavior
  3. Indication
    1. Short term (12 weeks per year) Obesity Management
    2. Physician discretion for indication to continue
  4. Classifications
    1. DEA Controlled Substance
      1. Class IV (Limited dependence liability)
  5. Dosing
    1. Start: 8 mg orally three times daily
    2. Alternative: 15 to 37.5 mg orally daily 10 hours before sleep
Medication Costs
phentermine (on 5/17/2017 at Medicaid.Gov Pharmacy Drug pricing)
PHENTERMINE 15 MG CAPSULE Generic $0.21 each
PHENTERMINE 30 MG CAPSULE Generic $0.19 each
PHENTERMINE 37.5 MG CAPSULE Generic $0.20 each
PHENTERMINE 37.5 MG TABLET Generic $0.11 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

Phentermine (C0031447)

Definition (NCI) A natural monoamine alkaloid derivative and a sympathomimetic stimulant with appetite suppressant property. Phentermine, which was part of the Fen-Phen anti-obesity medication, stimulates hypothalamic release of norepinephrine, a neurotransmitter involved in stress responses (fight-or-flight reactions), and reduces hunger sensation. Phentermine also causes the release of epinephrine or adrenaline outside of the brain, resulting in breakdown of stored fat.
Definition (MSH) A central nervous system stimulant and sympathomimetic with actions and uses similar to those of DEXTROAMPHETAMINE. It has been used most frequently in the treatment of obesity.
Definition (CSP) central nervous system stimulant and sympathomimetic with actions and uses similar to dextroamphetamine; used in the treatment of obesity.
Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH D010645
SnomedCT 373343009, 53480001
LNC LP16250-0, MTHU006735
English Phentermine, Benzeneethanamine, alpha,alpha-dimethyl-, phentermine, Phentermine [Chemical/Ingredient], 1,1-Dimethyl-2-phenylethylamine, 2-Phenyl-tert-butylamine, 2-Amino-2-methyl-1-phenylpropane, PHENTERMINE, Phenyl-tertiary-butylamine, Phentermine (product), Phentermine (substance)
Swedish Fentermin
Czech fentermin
Finnish Fentermiini
Japanese フェンテルミン, フェンテルミン塩酸塩, デュロミン, 塩酸フェンテルミン, イオナミン
Polish Fentermina
Spanish fentermina (producto), fentermina (sustancia), fentermina, Fentermina
French Phentermine
German Phentermin
Italian Fentermina
Portuguese Fentermina
Derived from the NIH UMLS (Unified Medical Language System)

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