Endocrinology Book

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Follicle Stimulating Hormone

Aka: Follicle Stimulating Hormone, Serum FSH
  1. See Also
    1. Luteinizing Hormone
  2. Physiology
    1. Follicle Stimulating Hormone (FSH) is a glyoprotein secreted by Basophil cells in the anterior Pituitary Gland
      1. Stimulation (releasing factors)
        1. Hypothalamic Gonadotrophic Releasing Hormone (GnRH)
      2. Inhibition (negative feedback loop to Hypothalamus and Pituitary Gland)
        1. Testosterone (Males)
        2. Estrogen
        3. Progesterone
        4. Inhibin
          1. Produced by corpus luteum in women
          2. Produced by spermatogenesis in men
    2. Follicle Stimulating Hormone (FSH) effects in women
      1. Stimulates ovarian follicle growth
        1. Ovarian follicle then secretes Estradiol
      2. Functions in concert with LH which stimulates ovarian follicles to ovulate and mature into a corpus luteum
        1. Corpus luteum in turn secretes Estrogen and Progesterone
    3. Follicle Stimulating Hormone (FSH) effects in men
      1. Stimulates spermatogenesis and sperm maturation within Sertoli Cells
      2. Functions in concert with LH which stimulates Leydig Cells within Testes to produce Testosterone
  3. Labs: Normal Levels
    1. Male: <20 mIU/ml
    2. Female: <25 mIU/ml (Higher in mid-cycle surge)
    3. Menopause: 30 to 250 mIU/ml
    4. Indications
      1. Not necessary to confirm Menopause diagnosis

Follicle Stimulating Hormone (C0733758)

Definition (NCI_NCI-GLOSS) A hormone made in the pituitary gland. In females, it acts on the ovaries to make the follicles and eggs grow. In males, it acts on the testes to make sperm.
Definition (MSH) A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.
Definition (CSP) major gonadotropin secreted by the anterior pituitary gland; stimulates gametogenesis and the supporting cells such as the ovarian granulosa cells and the testicular sertoli and leydig cells; FSH consists of two noncovalently linked subunits, alpha and beta; within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.
Concepts Hormone (T125) , Amino Acid, Peptide, or Protein (T116) , Pharmacologic Substance (T121)
MSH D005640
SnomedCT 90254006, 25217009, 325781003
LNC LP14499-5, LP32053-8, MTHU003493
English Follicle Stimulating Hormone, Follicle-Stimulating Hormone, Follitropin, follicle stimulating hormone, Follicle-stimulating hormone, FSH - Follic-stimulat hormone, FSH - Follicle stimulating hormone, FSH-Follicle stim horm, Follitropin (FSH), follitropin, Follicular stimulating hormone, FOLLITROPIN, Follicle Stimulating Hormone [Chemical/Ingredient], follicle hormone stimulating, follicle hormones stimulating, follicle stimulating fsh hormone, follicular stimulating hormone, follicular hormones stimulating, fshs, Follicle stimulating hormone preparation (product), FSH (Follicle Stimulating Hormone), follicle-stimulating hormone, FSH, Pituitary follicle stimulating hormone, Follicle stimulating hormone, Pituitary follicle stimulating hormone (substance), FSH - Follicle-stimulating hormone, FSH preparation, Follicle stimulating hormone preparation, Follicle-stimulating horm prod, Follitropin preparation, Follicle-stimulating hormone product (product), Follicle-stimulating hormone product, Follicle stimulating hormone preparation (substance), Follicle-stimulating horm prod (product), Follicle-stimulating horm prod (substance), FOLLICLE STIMULATING HORMONE
Swedish Follikelstimulerande hormon
Czech FSH, folikuly stimulující hormon
Finnish Follitropiini
French FSH (Follicle stimulating hormone), Follitropine, Folliculostimuline, Gonadostimuline A, Hormone folliculo-stimulante, Hormone folliculostimulante, Hormone gonadotrope A
Russian FSG, FOLLIKULOSTIMULIRUIUSHCHII GORMON, FOLLITROPIN, ФОЛЛИКУЛОСТИМУЛИРУЮЩИЙ ГОРМОН, ФОЛЛИТРОПИН, ФСГ
Spanish hormona foliculoestimulante (producto), hormona foliculoestimulante, hormona foliculoestimulante, producto, producto con hormona foliculoestimulante (producto), FSH, producto con hormona foliculoestimulante, foliculotrofina, hormona foliculostimulante, hormona hipofisaria foliculoestimulante (sustancia), hormona folículo - estimulante, hormona hipofisaria folículo - estimulante (sustancia), folitropina, hormona hipofisaria folículo - estimulante, hormona hipofisaria foliculostimulante, hormona hipofisaria foliculoestimulante, preparado de FSH, preparado de hormona folículo-estimulante (producto), preparado de hormona folículo-estimulante, Hormona Foliculoestimulante, Hormona Estimulante del Folículo, FSH, producto, folitropina, producto, hormona foliculoestimulante, producto (producto), hormona folículo - estimulante, producto, preparado de hormona folículo-estimulante (sustancia), HFE (Hormona Folículo Estimulante), Hormona Folículo Estimulante
Polish Folitropina, Gonadotropina pęcherzykowa, FSH, Folikulostymulina, Hormon luteotropowy
Japanese 卵胞刺激ホルモン, 向卵胞ホルモン, フォリトロピン, プロランA, 濾胞刺激ホルモン, 濾胞成熟ホルモン
Norwegian Follikkelstimulerende hormon, FSH, Follitropin
Portuguese Hormônio Foliculoestimulante, Hormônio Estimulante do Folículo, FSH (Hormônio Foliculoestimulante)
German Follikel-stimulierendes Hormon, FSH (Follikel-stimulierendes Hormon)
Italian FSH
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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