//fpnotebook.com/
Diffuse Axonal Injury
Aka: Diffuse Axonal Injury
- Pathophysiology
- Severe Traumatic Brain Injury from rotational acceleration and deceleration forces
- Affects the grey matter-white matter junctions
- Signs
- Severe Head Injury (high velocity impact or deceleration injury)
- Coma or severe confusion
- Glasgow Coma Scale (GCS) 8 or less
- Autonomic Dysfunction
- Fever
- Hypertension
- Diaphoresis
- Imaging
- CT Head
- Diffuse cerebral swelling
- White matter blends into gray
- Punctate Hemorrhages
- MRI Brain
- Punctate Hemorrhages within white matter tracts
- Management
- Neurosurgery Consultation
- Intracranial Pressure monitoring and other neurosurgical intervention may be indicated
- References
- Carney (2017) Neurosurgery 80(1): 6-15 [PubMed]