Emergency Medicine Book


Hemorrhagic Shock

Aka: Hemorrhagic Shock, Hemorrhage Evaluation, Hemorrhage, Hemorrhage Management, Exsanguination, Massive Hemorrhage, Large Volume Hemorrhage
  1. See Also
    1. Massive Blood Transfusion
    2. Fluid Resuscitation in Trauma
    3. Hemorrhage Classification
    4. Trauma Primary Survey
    5. Trauma Secondary Survey
    6. Pediatric Trauma
    7. ABC Management (Cardiopulmonary Resuscitation)
    8. Emergency Procedure
    9. Upper Gastrointestinal Bleeding
    10. Lower Gastrointestinal Bleeding
    11. Hemoptysis
    12. Uterine Bleeding in Pregnancy
  2. Epidemiology
    1. Hemorrhage is the leading cause of Trauma related death (typically within hours of presentation)
  3. Pathophysiology
    1. Significant Blood Volume loss causes impaired Oxygen Delivery
    2. With Hypoxemia, cellular metabolism relies on anaerobic glycolysis; Lactic Acid is produced with Metabolic Acidosis
    3. Tissue swelling and cell death result from proinflammatory mediator release, vascular endothelial cell injury
    4. Compensatory endogenous Catecholamines result in Tachycardia, increased Cardiac Output, and Vasoconstriction
    5. Compensation ultimately fails leading to cardiovascular collapse
  4. Precautions
    1. Recognize and definitively manage signs of shock early (see above)
      1. Most cases are Hemorrhagic Shock in the Trauma patient
      2. Paramount to locate and stop the source of bleeding (and replace losses)
    2. Comprehensive examination of the patient may be best evaluation tool in Hemorrhagic Shock
      1. Check distal extremity warmth and pulses
      2. Continue to assess occult bleeding sites (see causes of below)
    3. Hemorrhage Classification is a documentation and coding tool (not a Hemorrhage Management tool)
      1. Degree of Hemorrhage is often difficult to quantify or grade until retrospect
      2. Do not delay definitive management before patient meets a precise classification
    4. Vital Signs are a poor predictor of degree of Hemorrhage
      1. Shock Index (by contrast with Vital Signs) does correlate with degree of Hemorrhage
        1. Mutschler (2013) Crit Care 17(4): R172 [PubMed]
      2. Blood Pressure is unreliable for reassurance in a Trauma patient
        1. Frequently repeat Blood Pressure readings during Resuscitation
        2. Blood Pressure is the last hemodynamic marker to fall
          1. Vasoconstriction and Tachycardia are earlier compensation
        3. Hypotension in Trauma suggests Class III Hemorrhage or worse (>30% blood loss)
        4. Narrowed Pulse Pressure is a better marker in shock (Vasoconstriction increased DBP)
      3. Heart Rate may also be unreliable for reassurance in a Trauma patient
        1. See Delayed Tachycardia
        2. Patient may have lost ability to mount a tachycardic response (e.g. Beta Blocker use)
        3. Athletic fitness
        4. Autonomic Dysfunction may limit compensatory Tachycardia reflex
        5. Abdominal Hemorrhage may cause vagal response (Bezold-Jarisch)
      4. References
        1. Guly (2010) Resuscitation 81(9): 1142-7 +PMID: 20619954 [PubMed]
  5. Risk Factors: Massive Hemorrhage (requiring Massive Transfusion)
    1. Assessment of Blood Consumption Score (ABC Hemorrhage Score) >2
    2. Positive Focused Assessment Sonography for Trauma (FAST)
    3. Hypotension with Blood Pressure 90 mmHg or less
    4. Tachycardia with Heart Rate 120 bpm or higher
    5. Penetrating Injury
    6. Elevated serum Lactic Acid
    7. Low End-Tidal CO2
      1. End-Tidal CO2 may also be moderately reduced in Hyperventilation
      2. Very low End-Tidal CO2 (<15) suggests poor perfusion
      3. Stone (2017) Injury 48(1): 51-7 [PubMed]
  6. Causes
    1. Trauma (most common)
      1. Blunt Trauma
      2. Penetrating Trauma
    2. Atraumatic Hemorrhage
      1. Abdominal Aortic Aneurysm rupture
      2. Pulmonary Hemorrhage (e.g. Lung Cancer, Bronchiectasis, Tuberculosis)
      3. Upper Gastrointestinal Bleeding (e.g. Esophageal Varices, Peptic Ulcer Disease)
      4. Lower Gastrointestinal Bleeding (e.g. Diverticular Hemorrhage, angiodysplasia, aortoenteric fistula)
      5. Uterine Bleeding in Pregnancy (e.g. Ectopic Pregnancy, Placental Abruption, Placenta Previa)
  7. Causes: Hemorrhage Compartments (Mnemonic: "Blood on the floor, and 4 more")
    1. External sites and scalp
    2. Occult Traumatic Hemorrhage sites
      1. Chest
      2. Pelvis
      3. Abdomen (and Retroperitoneum)
      4. Thigh and long bones
  8. History: Bleeding Source
    1. Trauma
      1. Chest Trauma
      2. Abdominal Trauma
      3. Penetrating Trauma (Gunshot Wound, Stab Wound)
      4. Pelvic Fracture
      5. Femur Fracture
      6. Obstetrical Trauma
      7. Motor Vehicle Accident
      8. Scalp Laceration
    2. Non-Traumatic Sources
      1. Epistaxis
      2. Hemoptysis
      3. Hematemesis
      4. Melana, Maroon Stool or Hematochezia
      5. Vaginal Bleeding
  9. Symptoms
    1. Generalized weakness
    2. Syncope
    3. Altered Mental Status or Confusion
    4. Lethargy
  10. Exam
    1. See Shock
    2. See Trauma Evaluation
    3. Complete Trauma Evaluation
      1. Sources of bleeding (chest, Abdomen, Pelvis, retroperineum, long bones)
      2. Completely expose the patient (Mnemonic: Armpits, Back and Breasts, Butt cheeks and Sac)
      3. Evaluate for Scalp Lacerations, Epistaxis (including posterior bleeding)
      4. Evaluate for flank Ecchymosis, Scrotal Swelling, pulsatile abdominal mass, unstable Pelvis
    4. Reassess frequently
      1. Young healthy patients may with little warning, precipitously decompensate into cardiovascular collapse
    5. Tachycardia
      1. See Heart Rate for normal ranges for age
      2. Early warning sign of shock in most cases
      3. Cold and tachycardic is shock until proven otherwise
      4. However Heart Rate can be misleadingly normal in cases of Delayed Tachycardia (see above)
    6. Urine Output
      1. Normal Urine Output is >0.5 ml/kg/h in adults (>1 ml/kg/h in children, >2 ml/kg/h in infants)
    7. Arterial Injury Findings
      1. Hard Signs
        1. Pulsatile Bleeding
        2. Absent distal pulses
        3. Expanding hematoma
        4. Arterial Bruit
        5. Arterial thrill
      2. Soft Signs
        1. Initial pulsatile bleeding at prehospital evaluation
          1. Resolution of pulsatile bleeding does not exclude arterial bleeding
          2. Arterial spasm after injury may obscure hard arterial injury findings
        2. Non-expanding hematoma
        3. Neurologic deficits
        4. Close proximity of wound to major vessels
  11. Labs
    1. See Shock
    2. Complete Blood Count with Platelet Count
      1. First Hemoglobin is unreliable within first 8 hours of Hemorrhage (provides baseline for trending)
    3. Venous Blood Gas
      1. Degree of Metabolic Acidosis may help grade shock severity
    4. Coagulation Pathway Labs (INR, aPTT)
    5. Type and Crossmatch for Blood
    6. Ionized Calcium
      1. Hypocalcemia may decrease hemodynamics and increase Coagulopathy
    7. Pregnancy Test (urine HCG or serum HCG)
    8. Other tests
      1. Thromboelastography (TEG/ROTEM)
        1. Measures viscoelastic blood properties which may help guide transfusions
  12. Diagnostics
    1. Electrocardiogram (EKG)
      1. Cardiac Contusion
      2. Demand Myocardial Ischemia
    2. Other measures
      1. Diagnostic Peritoneal Lavage (DPL)
        1. Largely replaced by Bedside Ultrasound in U.S.
  13. Imaging
    1. Focused Assessment with Sonography for Trauma (eFAST)
      1. Free fluid within Abdomen or Pelvis
      2. Pericardial Effusion or Cardiac Tamponade
      3. Hemothorax
      4. Pneumothorax
    2. Rapid Ultrasound in Shock (RUSH Exam, "Pump, Tank and Pipes")
      1. Pump Evaluation (Cardiac Systolic Function)
      2. Tank Evaluation (Vascular volume status)
        1. See Inferior Vena Cava Ultrasound for Volume Status
      3. Pipes Evaluation (Large vessel integrity)
        1. See Abdominal Aorta Ultrasound
    3. Chest XRay (portable)
      1. Hemopneumothorax
    4. Pelvis XRay (portable)
      1. Pelvic Fracture
    5. Femur or Hip XRay (or other Long Bone XRay)
      1. Obtain as indicated
    6. CT Chest AbdomenPelvis with IV contrast (if stable enough)
      1. Consider with CT Angiography for vascular injury
      2. May identify bleeding source and targets for surgical or endovascular management
    7. CT Spine
      1. Consider if Neurogenic Shock suspected
    8. CT Angiography
      1. Consider in suspected extremity arterial injury
  14. Differential Diagnosis
    1. Cardiogenic Shock
      1. Tension Pneumothorax
      2. Cardiac Tamponade
    2. Neurogenic Shock secondary to spinal cord injury
      1. Neurogenic Shock does not occur in isolated intracranial injury
    3. Other non-Traumatic shock
      1. See Shock for Undifferentiated Shock approach
      2. Hypovolemic Shock (e.g. Dehydration)
      3. Septic Shock
  15. Evaluation
    1. Hemorrhage Classification (Class I-IV) is unreliable
      1. See Hemorrhage Classification
    2. Shock Index
      1. Shock Index = (Heart Rate) / (Systolic Blood Pressure)
      2. Shock Index >0.9 predicts need for increased transfusion requirements and early mortality risk
    3. Assessment of Blood Consumption Score (ABC Hemorrhage Score)
      1. Four point score (Penetrating Trauma, SBP<90 mmHg, Heart Rate>120, positive FAST Exam)
      2. ABC Hemorrhage Score 3 or 4 predicts Massive Transfusion protocol
    4. Trauma Associated Severe Hemorrhage (TASH)
      1. Based on SBP, pulse, gender, Hemoglobin, FAST Exam, Base Excess and pelvic/Femur Fracture
      2. Yucel (2006) J Trauma 60(6):1228-36 +PMID:16766965 [PubMed]
    5. McLaughlin Score
      1. Based on pulse >105 bpm, sbP <110 mmHg, pH<7.25, Hematocrit <32%
  16. Management: Hemorrhage Control
    1. Emergent Trauma surgery Consultation
      1. Poor response to Fluid Replacement or blood replacement indicates surgical management (or via angiography)
    2. Stop external bleeding immediately
      1. Apply direct manual pressure to external bleeding sites
      2. Pressure dressing may replace manual pressure if it adequately controls bleeding
        1. Israeli Bandage is elastic wrap with gauze impregnated with clotting agent
        2. Sanitary napkins or pads may also be used with overlying direct pressure at wound site
        3. Maintain direct pressure over bandage as needed to control bleeding
      3. Rapidly bleeding sites (e.g. Scalp Wounds) may be temporized with staples or Suture
      4. Consider occult Hemorrhage sources (see above)
      5. Bleeding refractory to manual pressure
        1. Notify Trauma surgery of emergent surgical intervention for rapid, uncontrolled bleeding
        2. Tourniquet (Pneumatic Tourniquet or Windlass Tourniquet)
          1. Indicated for rapid extremity bleeding not controlled with direct manual pressure
          2. Temporizing only until surgical intervention within 1-2 hours
          3. Permanent ischemic injury occurs if Tourniquet left in place >4-5 hours
          4. Ineffective in junctional sites (e.g. axilla, groin, adductor canal)
          5. Obviously unusable at neck and trunk
        3. Topical Hemostatic Agent (Chitosan Dressing, Zeolite Mineral Dressing, Kaolin Mineral Dressing)
          1. Indicated for rapid bleeding in sites where Tourniquets cannot be used (see above)
          2. Not widely available outside of military and large Trauma Centers as of 2013
          3. Risk of wound contamination with hemostatic agent
        4. Foley Catheter
          1. Inserted into a bleeding wound site
          2. Balloon inflated with Normal Saline
          3. May be effective at bleeding sites where Tourniquets may not be used
            1. Consider at junctional sites (e.g. groin, neck)
        5. XStat (RevMedX, limited efficacy and safety data)
          1. FDA approved for gun shot wounds in 2014
          2. Syringe filled with small, compressed cellulose sponges
          3. Syringe applicator inserted at exsanguinating gun shot wound
    3. Non-compressible Massive Hemorrhage
      1. Emergency Thoracotomy (in Cardiac Arrest)
        1. Massive chest Hemorrhage with CPR <15 min in Penetrating Trauma, CPR <10 min in blunt Trauma
      2. Resuscitative Endovascular Balloon Occlusion of the Aorta or REBOA (Peri-Arrest with systolic Blood Pressure <70 mmHg)
        1. Massive intraabdominal or pelvic Hemorrhage
      3. Pelvic Binder
        1. Unstable Pelvic Fracture with separation (e.g. open book or vertical sheer Pelvic Fracture)
        2. Apply binder empirically pre-imaging if Pelvic Fracture suspected in the Peri-Arrest, Hemorrhagic Shock patient
    4. Additional stabilization measures while temporizing until definitive surgical management
      1. Tranexamic Acid (Cyklokapron)
        1. Blocks plasmin formation (preventing Fibrinolysis)
        2. TXA 1 g IV load over 10 minutes, then 1 g IV over 8 hours
        3. May be indicated in first 1-3 hours following onset of Hemorrhage
          1. Consider when other measures fail and surgical intervention delayed
          2. Small mortality benefit in these cases
          3. Roberts (2011) Lancet 377(9771):1096-101 [PubMed]
      2. Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA)
        1. Percutaneous balloon delivered via groin catheter and inflated in aorta above level of Hemorrhage
        2. Indicated in severe bleeding Pelvic Fractures who have not had Cardiac Arrest
          1. Used as an immediate temporizing measures, pending emergent definitive surgical management
  17. Management: Volume Replacement
    1. Two large bore IVs (14 or 16 gauge if able, otherwise 18 gauge)
      1. Shorter tubing and larger bore provides faster IV rate
      2. Intraosseous Access if peripheral IV not immediately attainable
      3. Obtain Central Venous Line as available
        1. Large catheter introducer (8F or 9F) is preferred over multilumen
    2. Intravenous Fluids and Packed Red Blood Cells
      1. See Fluid Resucitation in Trauma
      2. Judicious use of crystalloid in Class II Hemorrhage or higher
        1. React to early signs and symptoms of acute blood loss with Hemorrhage control and blood replacement
        2. ATLS and textbooks still describe the use of NS or LR for 1-2 Liter bolus
        3. However, new practices suggest limiting crystalloid in favor of Blood Products (permissive Hypotension)
          1. Goal systolic Blood Pressure 80-100 mmHg
          2. IV fluids may artificially increase local pressure at non-compressible clot sites causing rebleeding
          3. IV fluids may dilute Coagulation Factors and Platelets
          4. Bickwell (1994) N Engl J Med 331(17): 1105-9 +PMID:7935634 [PubMed]
        4. Restrictive Resuscitation (permissive Hypotension) contraindications
          1. Prolonged transport time
          2. Transfer to Trauma Center
          3. Traumatic Brain Injury
          4. Hypotension, negative FAST Exam and normal Hemoglobin
        5. References
          1. Spanger and Inaba in Herbert (2015) EM:RAP 15(3):6-8
      3. Hemorrhage should be replaced with Blood Products
        1. Indications
          1. Mean arterial pressure 65 (or systolic Blood Pressure 70-90 mmHg)
            1. May need to target higher MAP (e.g. 80 mmHg) in Head Injury
          2. Poor response to IV fluids
            1. Persistent Tachycardia, Hypotension or Tachypnea
            2. Urine Output <50 ml/hour (<1ml/kg/hour)
        2. Start with 2-4 units (prepare at least 4 units pRBC for more severe Hemorrhage)
          1. Type specific blood can be ready within 30-40 minutes
          2. In the crashing patient give unmatched type-specific blood, Low titer O or O negative blood
            1. Men may be given O+ Blood
            2. Give RhoGAM prior to discharge if found to be Rh Negative (prevents future reactions)
        3. Massive Hemorrhage with administration of more than 4 units requires matching Blood Products
        4. Consider Autotransfusion (e.g. Hemovac or Cell Saver)
          1. Indicated for massive bleeding if blood can be drained and not contaminated)
        5. Use blood warmer when available
          1. Prevents Hypothermia with transfusion
  18. Management: Coagulopathy Correction
    1. Coagulopathy correction for Massive Blood Transfusion (>10 pRBC units within 24 hours)
      1. See Massive Blood Transfusion for protocol
      2. Massive Blood Transfusion is typically accompanied by Platelet and Plasma Transfusion
      3. Replace 1 unit of plasma for every 1-2 units of Packed Red Blood Cells
      4. Replace 1 unit of apheresis Platelets (6 pack equivalent) for every 8 units of Packed Red Blood Cells
      5. Consider Fibrinogen replacement to 1.5 to 2.0 g/L
      6. Prothrombin Complex Concentrate (PCC) 1-2 doses
        1. Do not use beyond 6-7 hours from bleeding onset (due to increased bleeding risk)
      7. Holcomb (2012) Arch Surg 15:1-10 [PubMed]
    2. Coagulopathy correction for underlying disorder or medication
      1. Reverse Anticoagulants
        1. See Emergent Reversal of Anticoagulation
        2. Platelet Transfusion for antiplatelet agents (e.g. Aspirin, Clopidogrel)
        3. Protamine for Heparin
        4. Vitamin K, FFP and PCC4 for Warfarin
      2. Specific management for Congenital Blood Coagulation Disorders
        1. Von Willebrand Disease
        2. Hemophilia A
        3. Hemophilia B (Factor IX Deficiency)
      3. Specific management for Acquired Blood Coagulation Disorders
        1. Cirrhosis
          1. Consider Vitamin K supplementation
          2. Decreased Anticoagulant and coagulant factors
            1. Therefore, not typically coagulopathic despite abnormal PT/INR and PTT
        2. Disseminated Intravascular Coagulation (DIC)
          1. Platelet Transfusion to Platelet Count >50,000/mm3
          2. FFP transfusion until PTT and PT/INR are each <1.5x normal
          3. Do not administer Tranexamic Acid (or other antifibrinolytic)
        3. Thrombotic ThrombocytopeniaPurpura
          1. Plasmaphoresis
        4. Drug induced Thrombocytopenia
          1. Withdraw offending medication
        5. End-stage renal disease
          1. Results in Anemia and Thrombocytopenia
          2. Hemodialysis
          3. Erythropoietin
          4. Cryoprecipitate
          5. Conjugated Estrogen
          6. Desmopressin
          7. Tranexamic Acid
  19. Management: Other measures and disposition
    1. Immediately stabilize and transfer to Trauma Center or to proper hospital service (e.g. Trauma service)
      1. Limit unnecessary studies that delay transfer
      2. Goal for disposition and transfer is 20 minutes
      3. Involve surgical consultants, intervention radiologists early
    2. Monitoring
      1. Vital Signs (Heart Rate, Blood Pressure, Pulse Pressure)
      2. Mental status
      3. Urine Output via urine catheter (unless suspected Urethral Trauma)
      4. Lactic Acid and Base Excess
    3. General measures
      1. ABC Management
      2. Prevent Hypothermia
      3. Continue to limit further bleeding
      4. Pelvic Binder (or bound bedsheet) for suspected unstable Pelvic Fracture
      5. Pregnant patients in left lateral decubitus position (see Trauma in Pregnancy)
      6. Replace Blood Products and prevent Coagulopathy (see above)
      7. Reverse hypoperfusion
      8. Continually reevaluate for concurrent injuries (e.g. Tension Pneumothorax, Cardiac Tamponade)
  20. Management: Damage Control Surgery Protocol
    1. Stage 0: Ground Zero (pre-hospital and emergency department)
      1. Rapid transfer to Trauma Center and operating room
      2. Stopping Hemorrhage is the primary priority
      3. Prevent Hypothermia
      4. Venous Blood Gas
    2. Stage 1: Initial Operation to control life threatening injuries and bleeding
      1. Control Hemorrhage
      2. Control contamination
      3. Judicious abdominal packing
      4. Rapid temporary abdominal closure
      5. Prevent Hypothermia
    3. Stage 2: ICU Resuscitation
      1. Resuscitation and monitor perfusion
      2. Correct acidosis and Coagulopathy
      3. Rewarm the patient
      4. Optimize oxygenation and ventilation
      5. Measure intraabdominal pressure
    4. Stage 3: Return for Definitive Repair in Operating Room in 12-24 hours
      1. Early reoperation for rebleeding
      2. Definitive surgical repair when patient physiologically stable
      3. Abdominal closure or staged closure
    5. References
      1. Rotondo (1993) J Trauma 35(3): 375-82 [PubMed]
      2. Johnson (2001) J Trauma 51(2): 261-71 [PubMed]
  21. Complications: Uncontrolled Hemorrhage
    1. Mortality
      1. Leading cause of death in both military and civilian Trauma
    2. Immediate Complications: Lethal Triad
      1. Hypothermia
      2. Metabolic Acidosis
      3. Coagulopathy
    3. Secondary Complications
      1. Sepsis
      2. Multi-system organ failure
  22. Complications: Massive Blood Transfusion
    1. Hypothermia
    2. Coagulopathy
    3. Metabolic Acidosis
    4. Electrolyte abnormalities
      1. Hypocalcemia
      2. Hyperkalemia
  23. References
    1. (2012) ATLS Manual, 9th ed, American College of Surgeons
    2. Kim, Tran, Lopez (2018) Crit Dec Emerg Med 32(12): 19-25
    3. Herbert and Alson in Herbert (2016) EM:Rap 16(2): 18
    4. Herbert (2012) EM:RAPC3 2(1): 1-2
    5. Ringhauser (2019) Crit Dec Emerg Med 33(6): 19-25
    6. Shinkle and Ponce (2016) Crit Dec Emerg Med 30(8): 13
    7. Swaminathan and Shoenberger (2021) EM:Rap 21(8): 1
    8. Swaminathan and van de Leuv (2013) Crit Dec in Emerg Med 27(8): 11-17
    9. Swadron and Inaba in Herbert (2014) EM:Rap 14(12): 5
    10. Weingart and Swaminathan in Herbert (2021) EM:Rap 21(3): 5-8

Hemorrhage (C0019080)

Definition (MEDLINEPLUS)

Bleeding is the loss of blood. It can happen inside or outside the body. Bleeding can be a reaction to a cut or other wound. It can also result from an injury to internal organs.

There are many situations in which you might bleed. A bruise is bleeding under the skin. Some strokes are caused by bleeding in the brain. Other bleeding, such as gastrointestinal bleeding, coughing up blood, or vaginal bleeding, can be a symptom of a disease.

Normally, when you bleed, your blood forms clots to stop the bleeding. Severe bleeding may require first aid or a trip to the emergency room. If you have a bleeding disorder, your blood does not form clots normally.

Definition (NCI_NCI-GLOSS) In medicine, loss of blood from damaged blood vessels. A hemorrhage may be internal or external, and usually involves a lot of bleeding in a short time.
Definition (NCI) The flow of blood from a ruptured blood vessel.
Definition (MSH) Bleeding or escape of blood from a vessel.
Definition (CSP) escape of blood from the vessels; bleeding.
Concepts Pathologic Function (T046)
MSH D006470
ICD9 459.0
ICD10 R58
SnomedCT 123106001, 303123004, 155459009, 195511004, 131148009, 50960005
LNC LA7418-2, LA7441-4
English Hemorrhages, Bleeding, Hemorrhage, HAEMORRHAGE NOS, HEMORRHAGE NOS, Haemorrhage NOS, Hemorrhage, unspecified, Hemorrhage NOS, hemorrhage, hemorrhage (diagnosis), bleeding (symptom), bleeding, Extravasation blood, Blood loss of (NOS), Haemorrhage, unspecified, Hem, Hemorrhage (NOS), Hemorrhage term, Hemorrhage [Disease/Finding], bleeding problem, bleeding problems, bleeds, hemorrhages, bleed, haemorrhages, blood loss, Haemorrhage NOS (disorder), Bleeding (disorder), Hemorrhage NOS (disorder), HEMORRHAGE, BLEEDING, Extravasation of blood, Blood loss, Haemorrhage, Hemorrhage (morphologic abnormality), Bleeding (finding), blood; extravasation, extravasation; blood, Bleeding, NOS, Haemorrhage, NOS, Hemorrhage, NOS, Bleeding -RETIRED-, haemorrhage
Italian Stravaso di sangue, Emorragia NAS, Emorragia (NAS), Emorragia terminale, Emorragia, non specificata, Fuoriuscita di sangue dai vasi sanguigni, Fuoriuscita di sangue, Perdita ematica, NAS, Sanguinamento, Emorragia
Dutch niet-gespecificeerde bloeding, hem, bloedingsperiode, bloeding, niet-gespecificeerde hemorragie, bloedverlies (NAO), hemorragie NAO, hemorragie (NAO), bloed; extravasatie, extravasatie; bloed, extravasatie bloed, hemorragie, Bloeding
French Hémorragie SAI, Hémorragie, non précisée, Hém, Hémorragie terminée, Effusion sanguine SAI, HEMORRAGIE SAI, Extravasation sanguine, Hémorragie, Saignement
German Blutung, unspezifisch, Hem, Bluten, Blutverlust (NNB), Blutung (NNB), Blutung, term, Blutung NNB, BLUTUNG NNB, Austritt von Blut, Blutung, Hämorrhagie
Portuguese Hemorragia NE, Heme, Perda de sangue NE, Hemorragia de termo, HEMORRAGIA NE, Extravasão de sangue, Hemorragia, Sangramento
Spanish Pérdida de sangre (NEOM), Hemorragia NEOM, Hemorragia no especificada, Hem, Hemorragia (NEOM), HEMORRAGIA SE, sangrante (concepto no activo), Haemorrhage NOS, hemorragia, SAI, sangrante, hemorragia, SAI (trastorno), Hemorrhage NOS, Sangrado, extravasación de sangre, hemorragia (anomalía morfológica), hemorragia (hallazgo), hemorragia, sangrado, Extravasación sanguínea, Hemorragia, Sangramiento
Japanese 出血NOS, 出血(NOS), 血液溢出, ケツエキイツシュツ, シュッケツ, シュッケツNOS, ケツエキイッシュツ, シュッケツショウサイフメイ, 出血、詳細不明, 失血, 出血
Swedish Blödning
Czech hemoragie, krvácení, Ztráta krve z (NOS), Krevní výron, Krvácení, blíže neurčené, Krvácení (NOS), Krvácení, Hem, Krvácení NOS
Finnish Verenvuoto
Latvian Not Translated[Hemorrhage]
Polish Krwotok
Hungarian Vérzés k.m.n., Vérző, Vérzés, Vérzés (k.m.n.), Haemorrhagia, nem meghatározott, Hem, Vérzés ideje, Vérzés, nem meghatározott, Vér extravasatio, Vérvesztés (k.m.n.)
Norwegian Blødning, Hemoragi, Blødninger
Derived from the NIH UMLS (Unified Medical Language System)

Shock, Hemorrhagic (C0036982)

Definition (MSH) Acute hemorrhage or excessive fluid loss resulting in HYPOVOLEMIA.
Definition (CSP) hemorrhage decreases the mean systemic filling pressure, therefore decreasing venous return; as a result, the cardiac output falls below normal, and shock ensues.
Concepts Pathologic Function (T046)
MSH D012771
SnomedCT 355001
English Shock, Hemorrhagic, Hemorrhagic Shock, hemorrhagic shock, hemorrhagic shock (diagnosis), Shock, Hemorrhagic [Disease/Finding], haemorrhagic shock, Shock haemorrhagic, Shock hemorrhagic, Hemorrhagic shock, Haemorrhagic shock, Hemorrhagic shock (disorder)
Dutch hemorragische shock, shock hemorragisch, Hemorragische shock, Shock, hemorragische
German Schock haemorrhagisch, haemorrhagischer Schock, Haemorrhagischer Schock, Hämorrhagischer Schock, Schock, hämorrhagischer
Swedish Blödningschock
Japanese シュッケツセイショック, ショック-出血性, 出血ショック, 出血性ショック
Czech šok hemoragický, Hemoragický šok, Šok hemoragický
Finnish Verenvuotosokki
Spanish Shock Hemorrágico, Choque Hemorrágico, choque hemorrágico (trastorno), choque hemorrágico, shock hemorrágico, Shock hemorrágico
Polish Wstrząs krwotoczny
Hungarian Haemorrhagiás shokk, Sokk haemorrhagica, Haemorrhagiás shock, Vérzéses shock
Norwegian Hemoragisk sjokk, Blødningssjokk, Sjokk, hemoragisk
Portuguese Choque hemorrágico, Choque Hemorrágico
French Choc hémorragique
Italian Shock emorragico
Derived from the NIH UMLS (Unified Medical Language System)

Exsanguination (C0232100)

Definition (MSH) Rapid and extreme blood loss leading to HEMORRHAGIC SHOCK.
Definition (NCI) Extensive loss of blood due to internal or external hemorrhage.
Definition (NCI_FDA) Extensive loss of blood due to internal or external hemorrhage.
Concepts Pathologic Function (T046)
MSH D058734
SnomedCT 48149007
LNC LA17979-8
Japanese 失血, シッケツ
Czech Vykrvácení, vykrvácení, exsanguinace
English Exsanguination, Hemorrhage, Exsanguinating, Exsanguinating Hemorrhage, Exsanguinating Hemorrhages, Hemorrhages, Exsanguinating, exsanguination, Exsanguination [Disease/Finding], EXSANGUINATION, Total blood loss, Exsanguination (finding)
French Hémorragie exsanguinante, Exsanguination
German Ausbluten, Verbluten, Massivblutung
Italian Dissanguamento
Spanish Exsanguinación, exanguinación (hallazgo), exanguinación, pérdida sanguínea total, Exanguinación
Portuguese Exsanguinação
Hungarian Exsanguinatio
Polish Skrwawienie, Wykrwawienie
Norwegian Massivt blodtap, Exsanguinatio, Stort blodtap
Dutch exsanguinatie
Derived from the NIH UMLS (Unified Medical Language System)

Massive hemorrhage (C0333279)

Concepts Pathologic Function (T046)
SnomedCT 112648003
English massive bleeding, massive hemorrhage, blood loss massive, massive blood loss, Massive bleeding, Massive blood loss, Massive hemorrhage, Massive haemorrhage, Massive hemorrhage (morphologic abnormality)
Spanish hemorragia masiva (anomalía morfológica), hemorragia masiva, pérdida masiva de sangre, sangrado masivo
Derived from the NIH UMLS (Unified Medical Language System)

You are currently viewing the original 'fpnotebook.com\legacy' version of this website. Internet Explorer 8.0 and older will automatically be redirected to this legacy version.

If you are using a modern web browser, you may instead navigate to the newer desktop version of fpnotebook. Another, mobile version is also available which should function on both newer and older web browsers.

Please Contact Me as you run across problems with any of these versions on the website.

Navigation Tree