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Palforzia
Aka: Palforzia, Peanut Allergen Powder
- See Also
- Food Allergy
- Immunotherapy
- Indications
- Peanut Allergy Desensitization in ages 4 to 17 years old
- Goal to reduce severity of reactions (NOT to reintroduce peanuts into diet)
- Alternative to peanut oral Immunotherapy (performed by allergists)
- Efficacy
- Following 1 year of Desensitization, two thirds of children are expected to tolerate 2 peanuts without reaction
- Precautions
- Peanut free diet must be followed regardless of Desensitization
- Keep Epinephrine Autoinjector nearby (reactions will be more common during Desensitization)
- Disadvantages
- Cost: $890 per month
- Must be in office to start medication and at each titration up in dose
- Restart in clinic if >3 doses missed
- Dosing
- Risk Evaluation and Mitigation Strategy (REMS) required for prescribers
- Taken daily and gradually increasing doses
- References
- (2020) Presc Lett 27(10): 58