Otolaryngology Book

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Drug-Induced Olfactory Dysfunction

Aka: Drug-Induced Olfactory Dysfunction, Drug-Induced Gustatory Dysfunction, Altered Sensation of Smell due to Medication, Medication Causes of Disordered Sense of Smell, Medication Causes of Disordered Sense of Taste
  1. See Also
    1. Olfactory Dysfunction
    2. Taste Dysfunction
  2. Causes: Cardiovascular
    1. Angiotensin-Converting Enzyme Inhibitor (ACE Inhibitor)
    2. Angiotensin Receptor Blocker (ARB)
    3. Dihydropyridine Calcium Channel Blocker
    4. Diuretics
    5. Antiarrhythmics
    6. Lipid lowering agents
  3. Causes: Nasal Preparations
    1. Intranasal Zinc
    2. Nasal Sprays in general
  4. Causes: Antimicrobials
    1. Antibiotics
      1. Penicillin
      2. Tetracycline
      3. Metronidazole (Flagyl)
      4. Macrolides (e.g. Clarithromycin, Azithromycin, Erythromycin)
      5. Fluoroquinolone (e.g. Ciprofloxacin, Levofloxacin)
      6. Aminoglycosides
    2. Antifungals
      1. Terbinafine (Lamasil)
      2. Griseofulvin
    3. HIV Medications
      1. Protease Inhibitors
  5. Causes: Miscellaneous
    1. Chemotherapy
      1. Antiproliferative drugs (e.g. Cisplatin)
    2. Antirheumatic Drugs (e.g. Penicillamine)
    3. Antithyroid Medications
    4. Antidepressants
    5. Anticonvulsants
    6. Azelastine (Antihistamine)
    7. Zopiclone (for Insomnia)
  6. References
    1. Ackerman (1997) Pharmacotherapy 17(3): 482-96 [PubMed]
    2. Malaty (2013) Am Fam Physician 88(1): 852-9 [PubMed]
    3. Naik (2010) Eur J Intern Med 21(3): 240-3 [PubMed]

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