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Auralgan
Aka: Auralgan, Benzocaine with Antipyrine, U-polycosanol 410, Aurodex
- Background
- In U.S., FDA forced manufacturers to stop producing Auralgan, Aurodex, A/B Otic...
- FDA cited that these agents were unapproved and without evidence of benefit or safety
- http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm453348.htm
- Indications
- Otalgia
- Adverse Effects: Benzocaine related (in Aurodex)
- Contact Dermatitis
- Methemoglobinemia
- Precautions
- Risk of Methemoglobinemia
- Not recommended in age under 2 years
- Given lack of topical alternatives, age limit handicaps the Acute Otitis Media Observation protocol
- Avoid overuse and stop if topical reaction
- Benzocaine (in Aurodex) is a common cause of Contact Dermatitis
- Avoid "new" Auralgan containing U-polycosanol 410 (uproven benefit)
- Costs $150 instead of old generic version price of $2
- Write to allow pharmacist to substitute with Generic Drug (either Aurodex or Benzocaine with Antipyrine)
- Dosing
- Use 2-4 drops three to four times daily
- Reference
- (2014) Presc lett 21(6): 36
- (2008) Presc Lett 15(5): 26