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Allergic Triad
Aka: Allergic Triad, Aspirin Induced Asthma, Aspirin Allergy
- Definition
- Allergic constellation centered around Aspirin Allergy
- Associated Conditions
- Aspirin-induced Asthma
- Rhinorrhea
- Nasal Polyps
- Chronic Sinusitis
- Conjunctival edema
- Course
- Onset as perennial Vasomotor Rhinitis
- Develops into hyperplastic Rhinosinusitis, Nasal Polyps
- Causes
- Aspirin
- Cross-reactivity with NSAIDs
- Indomethacin
- Naproxen
- Ibuprofen
- Fenoprofen
- Mefenamic acid
- Phenylbutazone
- Management
- Avoid Aspirin and causative NSAIDs above
- Use safe alternative Analgesics instead
- Salsalate
- Acetaminophen
- Treat Aspirin-induced Asthma
- Leukotriene modifiers (e.g. Sinulair)