Dermatology Book

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Soaps

Aka: Soaps, Soap, Mild Soap, Disinfectants and Cleansers, Triclosan
  1. Preparations: Soap-free cleansers
    1. Cetaphil lotion
    2. Aquaril lotion
    3. SFC lotion
    4. Neutrogena (non-drying)
    5. Moisturel sensitive skin cleanser
  2. Preparations: Soaps Mild or Hypoallergenic
    1. Dove (unscented): Contains lotion
    2. Oil of Olay
    3. Purpose
    4. Basis Glycerin or superfatted
    5. Aveeno bar
    6. Alpha-Keri
    7. Neutrogena Dry Skin
      1. Bar does not last long (dissolves quickly in water)
  3. Preparations: Alcohol based hand sanitizer (Alcohol-Based Hand Rub or ABHR)
    1. Mechanism
      1. Ruptures Bacterial cell walls
      2. Does not kill Clostridium difficile spores (use soap and water)
      3. Does not increase Antibiotic Resistance (in contrast to antibacterial soaps with Triclosan and similar agents)
    2. Agents examples
      1. Purell
  4. Preparations: Antibacterial Soaps
    1. Precautions
      1. Antibacterial soaps (75% of household hand cleansers) contain Ticlosan antibiotic (or similar)
      2. Increased risk of Antibiotic Resistance
      3. Little evidence that antibiotics add any benefit over standard, plain soap and water
    2. Agent examples
      1. Lever 2000 (least irritating)
      2. Dial
      3. Safeguard
    3. Resources
      1. FDA Soaps and Washes
        1. http://www.fda.gov/Drugs/ResourcesForYou/Consumers/BuyingUsingMedicineSafely/UnderstandingOver-the-CounterMedicines/ucm378122.htm
  5. Preparations: Antiseptic Cleansers
    1. Povidone Iodine (Betadine)
    2. Hexachlorophene (Phisohex)
    3. Chlorhexadine (Hibiclens)
  6. Preparations: Too Harsh Soaps
    1. Irish Spring
  7. Preparations: Laundry Detergents
    1. Dreft (Diaper detergent)
      1. Mild and ingredients never change

Soap (C0037392)

Definition (MSH) Sodium or potassium salts of long chain fatty acids. These detergent substances are obtained by boiling natural oils or fats with caustic alkali. Sodium soaps are harder and are used as topical anti-infectives and vehicles in pills and liniments; potassium soaps are soft, used as vehicles for ointments and also as topical antimicrobials.
Concepts Lipid (T119) , Manufactured Object (T073)
MSH D012915
SnomedCT 25780000
English Soaps, Soap, soaps (medication), soaps, soap, Soap (substance), Soap, NOS, SOAP
French Savons
Swedish Tvålar
Czech mýdla
Finnish Saippuat
Russian MYLA, МЫЛА
Polish Mydła
Japanese アルカリ石けん, 石けん, 石鹸
Portuguese Sabonetes, Sabonete, Sabão, Sabões
Spanish jabón (sustancia), jabón, Jabones
German Seifen
Italian Saponi
Dutch Zeep, Zepen
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Triclosan (C0040958)

Definition (NCI) A polychloro phenoxy phenol with antibacterial and antifungal activity. Triclosan is added to toothpastes to prevent gingivitis and has been added to many household products for its topical antibiotic activity.
Definition (MSH) A diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic. It has some bacteriostatic and fungistatic action.
Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH D014260
SnomedCT 273957004, 255908001, 125577003, 387054001
English Triclosan, 2-Hydroxy-2',4,4'-trichlorodiphenyl Ether, Phenol, 5-chloro-2-(2,4-dichlorophenoxy)-, triclosan (medication), TRICLOSAN, Triclosan [Chemical/Ingredient], triclosan, 2,4,4'-Trichloro-2'-Hydroxydiphenyl Ether, Triclosan product, Triclosan (product), Triclosan (substance), Triclosan [dup] (substance)
Swedish Triklosan
Czech triklosan
Finnish Triklosaani
Russian TRIKLOZAN, IRGAZAN DP 300, ИРГАЗАН DP 300, ТРИКЛОЗАН
Japanese トリクロサン
Spanish triclosano, Triclosán, triclosano (producto), triclosano (sustancia), triclosán (producto), triclosán (sustancia), triclosán
Polish Triklosan
French Triclosan
German Triclosan
Italian Triclosano
Portuguese Triclosan
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Disinfectants and cleansers (C0358213)

Concepts Manufactured Object (T073)
SnomedCT 333163002, 373222005
English Disinfectants and cleansers, Disinfectants and cleansers (product), Disinfectants and cleansers (substance)
Spanish desinfectante y limpiador (producto), desinfectante y limpiador, desinfectantes y limpiadores (sustancia), desinfectantes y limpiadores
Sources
Derived from the NIH UMLS (Unified Medical Language System)


mild soaps (C2064815)

Concepts Lipid (T119) , Manufactured Object (T073)
English mild soaps (medication), mild soaps, mild soaps (Dove)
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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