//fpnotebook.com/
Eflornithine Cream
Aka: Eflornithine Cream, Vaniqa
- Indications
- Hirsutism: Removal of unwanted facial hair in women
- Pharmacology
- Irreversible inhibitor of ornithine decarboxylase
- Inhibits polyamine biosynthesis
- Decreases polyamine mediated cell division
- Prior systemic use for African Trypanosomiasis
- Peak systemic absorption <10 ng/ml
- Adverse Effects: Local irritation
- Stinging or burning
- Tingling
- Dosing (30 gram tube costs pharmacist $42)
- Apply thin layer to affected area bid
- Doses should be at least 8 hours apart
- Avoid washing area for 4 hours after application
- Efficacy
- Modestly effective in reducing unwanted facial hair
- Hair Growth recurs soon after stopping medication
- References
- (2000) Med Lett Drugs Ther 42(1089):96 [PubMed]