Dermatology Book

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Butenafine

Aka: Butenafine, Mentax
  1. See Also
    1. Topical Antifungal
    2. Tinea Infection
    3. Terbinafine
  2. Mechanism
    1. Naphthalenemethylamine derivative (similar to Terbinafine)
  3. Indications
    1. Refractory cutaneous Tinea Infections (e.g. Tinea Pedis, Tinea Cruris)
  4. Dosing
    1. Apply once daily for 14 days to a 2 cm area surrounding Skin Infection
    2. Note: Unlike other Topical Antifungals, once daily application is sufficient
  5. Advantages
    1. Shorter course (2 instead of 4 weeks) than Clotrimazole
    2. More convenient (once daily) than other Topical Antifungals
  6. Disadvantages
    1. Expensive
  7. Efficacy
    1. High tinea cure rates with a 2 week course
    2. At 4-8 weeks, no significant difference in cure as compared with Clotrimazole
  8. References
    1. Greer (1997) J Am Acad Dermatol 37(2 Pt 1):231-5 [PubMed]
    2. Singal (2005) J Dermatolog Treat 16(5-6):331-5 [PubMed]

butenafine (C0107497)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH C067594
SnomedCT 108923003, 373449007
English butenafine, butenafine [Chemical/Ingredient], BUTENAFINE, Butenafine (product), Butenafine (substance), Butenafine
Spanish butenafina (producto), butenafina (sustancia), butenafina
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Mentax (C0721666)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH C067594
English Mentax, butenafine hydrochloride (Mentax), mentax, Bertek brand of butenafine hydrochloride
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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