//fpnotebook.com/
Azelaic Acid
Aka: Azelaic Acid, Azelex
- See Also
- Acne Vulgaris Pharmacologic Management
- Indication
- Acne Vulgaris
- Mechanism
- Topical antibacterial, Keratolytic agent
- Efficacy
- Not as effective as originally thought
- Only mild effect
- Use as an adjunct to other treatment
- Dosing
- Apply twice daily
- Cream 20% (Azelex)
- Approved for Acne Vulgaris
- Gel 15% (Finacea)
- Approved for Acne Rosacea
- Much better bioavailability than Azelex
- Adverse Effects
- Hypopigmentation
- Less irritating than Tretinoin or Benzoyl Peroxide
- Pruritus
- Burning, stinging and tingling
- Local erythema
- Precautions
- Use caution in Acne Vulgaris patients with dark skin
- May cause Hypopigmentation
- Safety
- Pregnancy Category B
- Only category B Keratolytic agent