Dermatology Book

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Alpha-Hydroxy acid

Aka: Alpha-Hydroxy acid, Lac-Hydrin, Glycolic Acid
  1. Indications
    1. Dyshidrotic Eczema
    2. Xerotic Eczema
  2. Preparations
    1. Alpha-Hydroxy acid preparations
      1. Glycolic Acid (8%)
      2. Lactic Acid or Lac-Hydrin (8-12%)
      3. Urea (3-6%)
    2. Combination agents with Skin Lubricant
      1. Eucerin plus
      2. Lubriderm moisture recovery cream
  3. Mechanism
    1. Forces epidermal cells to produce keratin
    2. Keratin is softer and more flexible
    3. Keratin is less likely to crack and fissure
  4. Adverse Effects
    1. May burn for few minutes with first applications
    2. Do not replace or add to oil barrier
  5. Dosing
    1. Dry Skin
      1. Use once to twice per day for 3 weeks
      2. Taper frequency to 1-3 days per week
    2. Aging
      1. Apply 1-2 days each week

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