Dermatology Book


Soft Tissue Mass

Aka: Soft Tissue Mass, Soft Tissue Growth, Soft Tissue Neoplasm, Skin Mass, Skin Lump, Subcutaneous Mass
  1. See Also
    1. Sarcoma
    2. Bone Neoplasm
    3. Skin Nodule
    4. Cyst
    5. Plaque
  2. Causes: Benign Soft Tissue Mass
    1. General
      1. See Skin Nodule
      2. Lymphadenopathy
      3. Hematoma
      4. Lipoma
      5. Sebaceous Cyst (Epidermal Inclusion Cyst)
      6. Common Wart or Molluscum Contagiosum
      7. Dermatofibroma
      8. Foreign Body Granuloma
    2. Scalp
      1. See Scalp Dermatitis
      2. Pilar Cyst (Trichilemmal Cyst)
      3. Keloid
    3. Hands and Feet
      1. Digital Mucous Cyst
      2. Ganglion Cyst
      3. Morton's Neuroma
      4. Plantar Fibroma
      5. Tenosynovial Giant Cell Tumor (Giant cell tumor of tendon sheath)
      6. Foot Schwannoma
    4. Muscle
      1. Myositis Ossificans
      2. Intramuscular Myxoma
      3. Smooth Muscle Hamartoma
    5. Vascular
      1. Cystic Lymphangioma, Capillary Lymphangioma or Cavernous Lymphangioma
      2. Hemangioma
      3. Pyogenic Granuloma
      4. Nodular Vasculitis
    6. Rheumatologic
      1. See Cutaneous Signs of Rheumatic Disease
      2. Rheumatoid Nodule
      3. Gouty Tophi
      4. Erythema Nodosum
      5. Polyarteritis Nodosa
    7. Infectious
      1. Skin Abscess
      2. Nodular Lymphangitis
      3. Tuberculous Lymphadenitis
      4. Mycetoma
    8. Congenital
      1. See Cutaneous Signs of Dysraphism
      2. See Neurocutaneous Syndrome (e.g. Neurofibromatosis)
  3. Causes: Malignant Soft Tissue Mass
    1. Sarcoma
      1. Dermatofibrosarcoma Protuberans
      2. Leiomyosarcoma
      3. Liposarcoma
      4. Rhabdomyosarcoma
      5. Synoviosarcoma
    2. Other malignancy that may involve soft tissue
      1. Lymphoma
      2. Squamous Cell Carcinoma
      3. Basal Cell Carcinoma
      4. Melanoma
  4. Precautions: Red flags for Malignancy
    1. Firm, deep masses adherent to adjacent structures
    2. Large lesions >5 cm in diameter (golf ball size)
      1. Accounts for 90% of malignant lesions
      2. However, diameter <5 cm does not exclude malignancy
    3. Consistent size between days (e.g. Sarcoma)
      1. Some benign masses (e.g. Ganglion Cysts, Hemangiomas) fluctuate in size
    4. Soft Tissue Masses in childhood
      1. Children are less likely to have Lipomas or Sebaceous Cysts
  5. Exam
    1. Palpate lesion for size, mobility, consistency and attachment to deep structures
  6. Imaging
    1. Ultrasound (POCUS or formal Ultrasound)
      1. High frequency linear probe
      2. Identifies tumor size, margins, depth, vascularity and consistency (e.g. cystic)
      3. Excellent first line, low cost study that can expedite evaluation (esp. POCUS)
    2. MRI
      1. Most accurate imaging modality to evaluate Soft Tissue Masses and adjacent structures
      2. Also identifies necrosis, borders and relationship to fascial planes
    3. CT
      1. Consider in adults unable to undergo MRI
      2. Offers less soft tissue definition than MRI, but can identify bone and vessels, lesion density, calcifications
  7. Evaluation
    1. Refer suspicious lesions for further evaluation (e.g. needle core biopsy)
    2. Typical benign lesions may be excised per patient preference
      1. Send excised lesions for pathology
  8. References
    1. Achar (2022) Am Fam Physician 105(6): 602-12 [PubMed]

Mass of skin (C0281981)

Concepts Finding (T033)
SnomedCT 297960002
English skin lump (symptom), skin lump, lump in/on the skin, skin lump:, lump in or on skin, lump in or on skin (symptom), lump in / on the skin, lumps skin, lump skin, skin mass, Cutaneous mass, Skin mass, Lump of skin, Mass of skin, Mass of skin (finding)
Spanish Masa cutánea, masa cutánea (hallazgo), masa cutánea
Dutch huidgezwel
German Raumforderung der Haut
Japanese 皮膚腫瘤, ヒフシュリュウ
Czech Kožní hmota
Portuguese Massa cutânea
Italian Massa cutanea
French Masse cutanée
Hungarian Bőr tömeg
Derived from the NIH UMLS (Unified Medical Language System)

Soft tissue mass (C0457193)

Concepts Anatomical Abnormality (T190)
SnomedCT 444905003, 278002000
English Mass of soft tissue, Mass of soft tissue (finding), soft tissue mass, masses soft tissue, Soft tissue mass, Soft tissue mass (morphologic abnormality)
Spanish masa de partes blandas (hallazgo), Masa de tejidos blandos, masa de partes blandas (anomalía morfológica), masa de partes blandas
Portuguese Massa de tecidos moles
Italian Massa di tessuto molle
German Raumforderung des Weichgewebes
French Masse des tissus mous
Dutch weke delen gezwel
Czech Rezistence měkké tkáně
Japanese 軟部組織腫瘤, ナンブソシキシュリュウ
Hungarian Lágyszövet tömeg
Derived from the NIH UMLS (Unified Medical Language System)

Mass of subcutaneous tissue (C3670836)

Concepts Finding (T033)
SnomedCT 309011000009106
English Mass of subcutaneous tissue (finding), Subcutaneous tissue mass, Mass of subcutaneous tissue
Derived from the NIH UMLS (Unified Medical Language System)

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