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Pemphigus
Aka: Pemphigus, Intraepidermal Blister- See Also
- Definition
- IntraepidermalAcantholyticBlister
- Mnemonic: Pemphigus ends in S for Superficial
- Contrast with the deeper Pemphigoid
- Types: Primary forms of Pemphigus
- Deep Pemphigus (above Basal Cell Layer of Epidermis)
- Pemphigus Vulgaris (most common and most severe)
- Pemphigus Vegetans (rare Pemphigus Vulgaris variant)
- Drug-Triggered Pemphigus (umasks Pemphigus Vulgaris)
- Superficial Pemphigus (involves Stratum Granulosum)
- Deep Pemphigus (above Basal Cell Layer of Epidermis)
- Types: Secondary forms of Pemphigus
- Signs
- Flaccid Blister (superficial)
- Nikolsky's Sign
- Positive in Pemphigus Vulgaris
- Negative in Pemphigus Foliaceus (most superficial)
- Histology
- All Pemphigus conditions show epidermal Acantholysis