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Esmolol
Aka: Esmolol, Esmolol Hydrochloride, Brevibloc
- See Also
- Beta Blocker
- Mechanism
- Selective Beta Blocker
- Indications
- Atrial Fibrillation Rate Control
- Emergent Hypertension Management
- Pharmacokinetics
- Half-life: 9 minutes
- Rapidly metabolized by erythrocyte esterase
- Duration of action: 15-20 minutes
- Dosing: Intravenous
- Preparation: 2.5g (10 ml ampule) in 250 ml (10 mg/ml)
- Load: 250-500 ug/kg over 1 min (70 kg: 35 mg, 3.5 ml)
- Infusion:
- Start 25-50 ug/kg/min IV (70 kg: 10 ml/h)
- Titrate up 25-50 ug/kg q5 min to max 300 ug/kg/min