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Alpha Adrenergic Central Agonist
Aka: Alpha Adrenergic Central Agonist, Central Adrenergic Agonist, Methyl-Dopa, Methyldopa, Aldomet, Guanabenz, Wytensin- See Also
- Mechanism
- See Alpha Adrenergic Receptor
- Bind vasomotor receptors to inhibit sympathetic outflow
- Decreases peripheral vascular resistance (and Blood Pressure)
- Decreases Heart Rate
- Preparations
| Medication Costs | ||
|---|---|---|
| Methyldopa (on 6/18/2017 at Walmart.com) | ||
| Methyldopa 250mg | #60 tablets for $4.00 | $0.07 each |
| Methyldopa 250mg | #180 tablets for $10.00 | $0.06 each |
| methyldopa (on 5/17/2017 at Medicaid.Gov Pharmacy Drug pricing) | ||
| METHYLDOPA 250 MG TABLET | Generic | $0.10 each |
| METHYLDOPA 500 MG TABLET | Generic | $0.27 each |
| FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. | ||
Guanabenz (C0018312) |
|
|---|---|
| Definition (MSH) | An alpha-2 selective adrenergic agonist used as an antihypertensive agent. |
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | D006143 |
| SnomedCT | 372867002, 82951001 |
| English | 2,6-Dichlorobenzylideneaminoguanidine, Guanabenz, 2,6 Dichlorobenzylideneaminoguanidine, Hydrazinecarboximidamide, 2-((2,6-dichlorophenyl)methylene)-, guanabenz, Guanabenz [Chemical/Ingredient], GUANABENZ, Guanabenz (product), Guanabenz (substance) |
| Swedish | Guanabenz |
| Czech | guanabenz |
| Finnish | Guanabentsi |
| Russian | GUANABENZ, ГУАНАБЕНЗ |
| Japanese | グアナベンツ, グアナベンズ |
| Polish | Guanabenz |
| Spanish | guanabenz (producto), guanabenz (sustancia), guanabenz, Guanabenzo |
| French | Guanabenz |
| German | Guanabenz |
| Italian | Guanabenzo |
| Portuguese | Guanabenzo |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Wytensin (C0018313) |
|
|---|---|
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | D006143 |
| English | Wyeth-Ayerst of Guanabenz Acetate, Wyeth Ayerst of Guanabenz Acetate, Acetate Wyeth-Ayerst, Guanabenz, Guanabenz Acetate Wyeth-Ayerst, Wytensin |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Methyldopa (C0025741) |
|
|---|---|
| Definition (NCI) | A phenylalanine derivative and an aromatic amino acid decarboxylase inhibitor with antihypertensive activity. Methyldopa is a prodrug and is metabolized in the central nervous system. The antihypertensive action of methyldopa seems to be attributable to its conversion into alpha-methylnorepinephrine, which is a potent alpha-2 adrenergic agonist that binds to and stimulates potent central inhibitory alpha-2 adrenergic receptors. This results in a decrease in sympathetic outflow and decreased blood pressure. |
| Definition (MSH) | An alpha-2 adrenergic agonist that has both central and peripheral nervous system effects. Its primary clinical use is as an antihypertensive agent. |
| Concepts | Pharmacologic Substance (T121) , Neuroreactive Substance or Biogenic Amine (T124) , Amino Acid, Peptide, or Protein (T116) |
| MSH | D008750 |
| SnomedCT | 373542000, 84078002 |
| LNC | LP16200-5, MTHU016766 |
| English | Alphamethyldopa, alpha Methyl L Dopa, alpha Methyldopa, alpha-Methyl-L-Dopa, alpha-Methyldopa, methyldopa, L-Tyrosine, 3-hydroxy-alpha-methyl-, 3-Hydroxy-alpha-methyl-L-tyrosine, L-2-Amino-2-methyl-3-(3,4-dihydroxyphenyl)propionic Acid, Levo-3-(3,4-Dihydroxyphenyl)-2-methylalanine, O methyl DOPA, methyldopa (medication), Methyldopa [Chemical/Ingredient], alphamethyldopa, alpha-methyldopa, alpha methyldopa, METHYLDOPA, Methyldopa, Alpha methyldopa, Methyldopa (product), Methyldopa (substance) |
| Swedish | Metyldopa |
| Czech | methyldopa |
| Finnish | Metyylidopa |
| Russian | AL'FA-METILDOFA, METILDOPA, METILDOFA, METILDOPAT, АЛЬФА-МЕТИЛДОФА, МЕТИЛДОПА, МЕТИЛДОПАТ, МЕТИЛДОФА |
| Japanese | α-メチルドーパ, メチルドパ, メチルドーパ, アルファ-メチルドーパ |
| Spanish | alfa-Metildopa, metildopa (producto), metildopa (sustancia), metildopato, metildopa, Metildopa |
| French | alpha-Méthyldopa, alpha-L-Méthyldopa, Méthyldopa |
| Croatian | METILDOPA |
| Polish | Metylodopa |
| German | Alphamethyldopa, Methyldopa |
| Italian | Metildopa |
| Portuguese | alfa-Metildopa, Metildopa |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Central alpha-adrenoceptor agonist (C0360167) |
|
|---|---|
| Concepts | Pharmacologic Substance (T121) |
| SnomedCT | 349933002, 372623002 |
| English | Central alpha-adrenocep agon., Central alpha-adrenoceptor agonist, Central alpha-adrenoceptor agonist (product), Central alpha-adrenoceptor agonist (substance) |
| Spanish | agonista central alfa adrenérgico (producto), agonista central alfa adrenérgico (sustancia), agonista central alfa adrenérgico, agonista de adrenorreceptor alfa central (sustancia), agonista de adrenorreceptor alfa central |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Aldomet (C0591055) |
|
|---|---|
| Concepts | Pharmacologic Substance (T121) , Amino Acid, Peptide, or Protein (T116) |
| MSH | D008750 |
| English | aldomet, Aldomet, Biopat Brand of Methyldopa, Cahill May Roberts Brand of Methyldopa, Merck Brand of Methyldopa, Merck Sharp & Dohme Brand of Methyldopa, Methyldopa Biopat Brand, Methyldopa Merck Brand |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
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