Cardiovascular Medicine Book



Aka: Lipid, Cholesterol, Total Cholesterol
  1. See Also
    1. Hyperlipidemia
    2. Hyperlipidemia Management
    3. Hypertriglyceridemia
    4. CAD Risk Management
  2. Definitions
    1. Lipids
      1. Organic molecules containing hydrocarbons
      2. Examples include free Fatty Acids, Triglycerides, phospholipids
    2. Cholesterol
      1. Lipid precursor for steroid Hormones, bile acids and Vitamin D
  3. Precautions
    1. Total Cholesterol <175 mg/dl in elderly: Increased mortality
      1. Schupf (2005) J Am Geriatr Soc 53:219-26 [PubMed]
  4. Components
    1. LDL Cholesterol
    2. VLDL Cholesterol
    3. HDL Cholesterol
  5. Patient Education
    1. Mnemonic: Lower L-DL, Higher H-DL

Cholesterol (C0008377)

Definition (MEDLINEPLUS)

Cholesterol is a waxy, fat-like substance that occurs naturally in all parts of the body. Your body needs some cholesterol to work properly. But if you have too much in your blood, it can combine with other substances in the blood and stick to the walls of your arteries. This is called plaque. Plaque can narrow your arteries or even block them.

High levels of cholesterol in the blood can increase your risk of heart disease. Your cholesterol levels tend to rise as you get older. There are usually no signs or symptoms that you have high blood cholesterol, but it can be detected with a blood test. You are likely to have high cholesterol if members of your family have it, if you are overweight or if you eat a lot of fatty foods.

You can lower your cholesterol by exercising more and eating more fruits and vegetables. You also may need to take medicine to lower your cholesterol.

NIH: National Heart, Lung, and Blood Institute

Definition (NCI) An animal sterol found in the body tissues (and blood plasma) of vertebrates. It can be found in large concentrations within the liver, spinal cord, and brain. Cholesterol is an important component of the membranes of cells, providing stability. It is the major precursor for the synthesis of vitamin D, of the various steroid hormones, including cortisol, cortisone, and aldosterone in the adrenal glands, and of the sex hormones progesterone, estrogen, and testosterone. Cholesterol also has an important role for the brain synapses as well as in the immune system. In conditions featuring elevated low density lipoproteins (LDL), cholesterol often forms plaque deposits in the walls of arteries, a condition known as atherosclerosis, which is a major contributor to coronary heart disease and other forms of cardiovascular disease.
Definition (NCI_NCI-GLOSS) A waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid. Cholesterol also comes from eating foods taken from animals such as egg yolks, meat, and whole-milk dairy products. Too much cholesterol in the blood may build up in blood vessel walls, block blood flow to tissues and organs, and increase the risk of developing heart disease and stroke.
Definition (NCI_CRCH) Lipid composed of 27 carbon atoms which form three fused cycloheane (6-carbon) rings, a cyclopentane (5-carbon ring) and a side chain of 8 carbon atoms. (Ensminger et al).
Definition (MSH) The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Definition (CSP) C27H46O, the major fatty steroid alcohol of vertebrate animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Concepts Biologically Active Substance (T123) , Steroid (T110)
MSH D002784
SnomedCT 84698008
LNC LP15493-7, LP100019-1, MTHU003147
English Cholesterol, Cholest-5-en-3-ol (3beta)-, (3beta)-Cholest-5-en-3-ol, Cholesterol [Chemical/Ingredient], cholesterol, CHOLESTEROL, 5-cholesten-3B-ol, (-)-Cholesterol, Cholesterol (substance)
Swedish Kolesterol
Czech cholesterol
Finnish Kolesteroli
Japanese コレステリン, コレステロール
Polish Cholesterol
Spanish colesterol (sustancia), colesterol, Colesterol
French Cholestérol
German Cholesterol
Italian Colesterolo
Portuguese Colesterol
Derived from the NIH UMLS (Unified Medical Language System)

Hyperlipidemia (C0020473)

Definition (NCI) Elevated levels of lipids in the blood.
Definition (CSP) excess of lipids in the blood.
Definition (MSH) Conditions with excess LIPIDS in the blood.
Concepts Disease or Syndrome (T047)
MSH D006949
ICD10 E78.5
SnomedCT 154743001, 190782002, 154739000, 267499005, 55822004
English Hyperlipemia, Hyperlipemias, HYPERLIPAEMIA, Hyperlipidaemia NOS, Hyperlipidaemia, unspecified, Hyperlipidemia, unspecified, Hyperlipidemias, Hyperlipidemia NOS, hyperlipemia, hyperlipidemia (diagnosis), hyperlipidemia, Hyperlipaemia, Hyperlipidemias [Disease/Finding], lipidaemia, excessive fat in the blood, hyperlipidaemias, hyperlipidemias, lipidemia, Hyperlipidaemia NOS (disorder), Hyperlipidemia NOS (disorder), Disorder characterized by hyperlipidemia, Hyperlipidaemia, Lipidemia, HLD - Hyperlipidaemia, HLD - Hyperlipidemia, Hyperlipidemia (disorder), Lipidaemia, lipemia, lipoidemia, Hyperlipidemia, NOS, Hyperlipidaemia, NOS, Hyperlipidemia, hyperlipidaemia
Portuguese HIPERLIPEMIA, Hiperlipidemia NE, Hiperlipidemias, Hiperlipidemia, Hiperlipemia
Spanish HIPERLIPEMIA, Hiperlipidemia NEOM, Hiperlipidemias, hiperlipidemia, SAI (trastorno), hiperlipidemia, SAI, Hyperlipidaemia NOS, Hyperlipidemia NOS, hiperlipemia, hiperlipidemia (trastorno), hiperlipidemia, Hiperlipidemia, Hiperlipemia
Dutch hyperlipemie, hyperlipidemie NAO, Hyperlipidemie, niet gespecificeerd, hyperlipidemie
French Hyperlipidémie SAI, Hyperlipidémie, HYPERLIPEMIE, Hyperlipémies, Hyperlipidémies, Hyperlipémie
German Hyperlipaemie, Hyperlipidaemie NNB, HYPERLIPAEMIE, Hyperlipidaemie, nicht naeher bezeichnet, Hyperlipidaemie, Hyperlipämie, Hyperlipidämie
Italian Iperlipidemia NAS, Condizione iperlipidemica, Lipidi elevati, Valori lipidici elevati, Iperlipidemia, Iperlipemia
Japanese 高脂血症NOS, コウシケッショウNOS, コウシケッショウ, コウシケツショウNOS, コウシケツショウ, 高脂質血, 高脂血症, 脂血症, 脂肪過剰血, 脂質過剰血症, 脂肪血症, 高脂肪血症, リポイド過多血症, 高脂血症(コウシケツショウ), 脂質異常症, 高脂質血症
Swedish Hyperlipemier
Czech hyperlipémie, hyperlipidémie, Hyperlipidemie NOS, Hyperlipemie, Hyperlipidemie
Finnish Hyperlipidemiat
Korean 상세불명의 고지혈증
Polish Hiperlipidemia samoistna rodzinna, Hiperlipidemie
Hungarian Hyperlipidaemia, Hyperlipaemia, Hyperlipidaemia k.m.n.
Norwegian Høyt blodfett, Hyperlipidemier, Hyperlipemi, Hyperlipidemi
Derived from the NIH UMLS (Unified Medical Language System)

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