Jarisch-Herxheimer Reaction

Aka: Jarisch-Herxheimer Reaction

II. Pathophysiology

  1. Reaction occurs with treatment of Spirochete infection
    1. Syphilis (reaction occurs variably based on stage)
      1. Primary Syphilis: 50%
      2. Secondary Syphilis: 90%
      3. Latent Syphilis: 25%
    2. Relapsing Fever (Tick-Borne Disease)

III. Signs and Symptoms

  1. General
    1. Fever
    2. Adenopathy
    3. Skin rash
    4. Arthralgias
    5. Malaise
    6. Diaphoresis
  2. Neurologic symptoms
    1. Headache
    2. Seizures
    3. Cerebrovascular Accident

IV. Course

  1. Occurs 2 to 6 hours after treatment started
  2. Symptoms last for 24 hours

V. Management

  1. Acetaminophen 2 hours before and after antibiotic dose
  2. Corticosteroids and NSAIDs do not prevent complications

Images: Related links to external sites (from Bing)

These images are a random sampling from a Bing search on the term "Jarisch-Herxheimer Reaction." Click on the image (or right click) to open the source website in a new browser window. Search Bing for all related images

Related Studies

Ontology: Jarisch Herxheimer reaction (C0259756)

Concepts Injury or Poisoning (T037)
SnomedCT 10803007
English Herxheimer's reaction, Herxheimer reaction, Jarisch-Herxheimer reaction (diagnosis), Jarisch-Herxheimer reaction, herxheimer reaction, jarisch-herxheimer reaction, herxheimer's reaction, jarisch herxheimer reaction, herxheimer reactions, herxheimer jarisch reaction, Jarisch Herxheimer reaction, Jarisch Herxheimer reaction (disorder), Herxheimer; reaction, Herxheimer, reaction; Herxheimer
Italian Reazione di Jarisch-Herxheimer, Reazione di Herxheimer
Dutch Herxheimer-reactie, Herxheimer; reactie, reactie; Herxheimer, Jarisch-Herxheimer-reactie
German Herxheimer-Reaktion, Jarisch-Herxheimer-Reaktion
Portuguese Reacção de Herxheimer, Reacção de Jarisch-Herxheimer
Spanish Reacción de Herxheimer, reacción de Herxheimer (trastorno), reacción de Herxheimer, reacción de Jarisch Herxheimer (trastorno), reacción de Jarisch Herxheimer, Reacción de Jarisch-Herxheimer
Japanese ヤーリッシュ・ヘルクスハイマー反応, ヘルクスハイマー反応, ﾍﾙｸｽﾊｲﾏｰﾊﾝﾉｳ, ﾔｰﾘｯｼｭﾍﾙｸｽﾊｲﾏｰﾊﾝﾉｳ
French Réaction d'Herxheimer, Réaction de Jarisch-Herxheimer
Czech Jarisch-Herxheimerova reakce, Herxheimerova reakce
Hungarian Herxheimer-reakció, Jarisch-Herxheimer-reakció
Derived from the NIH UMLS (Unified Medical Language System)

Related Topics in Sexually Transmitted Disease

2021 Family Practice Notebook, LLC. Terms | Privacy (EHS) | About | Site Map | Blog

Footer Site Logo