Famciclovir

Aka: Famciclovir, Famvir

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II. Indications

  1. Herpes Zoster (Shingles)
  2. Recurrent Genital Herpes
  3. Recurrent HSV in immunocompromised patients

III. Dosing

  1. Herpes Zoster (Shingles)
    1. Adult: 500 mg PO q8 hours for 7 days
  2. Genital Herpes
    1. Initial: 250 mg PO tid for 7-10 days
    2. Recurrent immunocompetent: 125 mg PO bid for 5 days
    3. Recurrent in HIV: 500 mg PO bid for 7 days
    4. Prophylaxis: 250 mg PO bid for up to 12 months

IV. Pharmacokinetics

  1. Adjust dose for Creatinine Clearance <60 ml/min

V. Adverse Effects

  1. Headache
  2. Nausea or Vomiting
  3. Fatigue
  4. Paresthesias
  5. Pruritus

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Cost: Medications

famciclovir (on 12/21/2016 at Medicaid.Gov Survey of pharmacy drug pricing)
FAMCICLOVIR 125 MG TABLET Generic $0.80 each
FAMCICLOVIR 250 MG TABLET Generic $0.52 each
FAMCICLOVIR 500 MG TABLET Generic $0.97 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

Ontology: famciclovir (C0209227)

Definition (NCI) A diacetyl 6-deoxy prodrug analog of the antiviral agent penciclovir. Orally administered, famciclovir in vivo is converted to penciclovir triphosphate, which is active against the Herpes viruses, including herpes simplex 1 and 2 and varicella-zoster. This agent inhibits the replication of viral DNA by interfering competitively with DNA polymerase. (NCI04)
Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH C060590
SnomedCT 387557001, 96097002
LNC LP157326-2, MTHU045606
English 9-(4-acetoxy-3-(acetoxymethyl)but-1-yl)-2-aminopurine, famciclovir, famciclovir (medication), FAMCICLOVIR, famciclovir [Chemical/Ingredient], 2-(2-(2-Amino-9H-purin-9-yl)ethyl)-1,3-propanediol Diacetate (ester), Famciclovir, Famciclovir product, Famciclovir (substance), Famciclovir (product)
Spanish famciclovir (producto), famciclovir (sustancia), famciclovir
Derived from the NIH UMLS (Unified Medical Language System)

Ontology: Famvir (C0591478)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH C060590
English Famvir, famvir
Derived from the NIH UMLS (Unified Medical Language System)

Related Topics in Pharmacology

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