II. Indications
-
Influenza
- Alternative to Oseltamivir (Tamiflu)
III. Mechanism
IV. Dosing
- One single oral dose
V. Efficacy
- May shorten Influenza symptoms by up to 1 day if started within 48 hours
- No evidence for benefit in high risk patients (under age 2, over age 65, pregnancy)
VI. Adverse Effects (in 1-3% of patients)
VII. Drug Interactions
- Agents that decrease absorption (e.g. calcium, aluminum or iron salts)
VIII. References
- (2018) Presc Lett 25(12): 67
