Adefovir

Aka: Adefovir, Preveon

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II. Mechanism

  1. Nucleoside Reverse Transcriptase Inhibitor

III. Dosing

  1. Adefovir 120 mg PO qd
  2. Take with L-carnitine 500 mg supplement

IV. Adverse Effects

  1. Nephrotoxicity (30%)
    1. Fanconi Syndrome like condition
  2. Nausea
  3. Diarrhea
  4. Asthenia
  5. Liver Function Test abnormalities

V. Availability

  1. Phone: 1-800-445-3235

VI. References

  1. (1998) Med Lett Drugs Ther 40(1041):115 [PubMed]
  2. (2009) Treat Guidel Med Lett 7(78): 11-22 [PubMed]

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Cost: Medications

adefovir (on 5/17/2017 at Medicaid.Gov Survey of pharmacy drug pricing)
ADEFOVIR DIPIVOXIL 10 MG TAB Generic $24.21 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

Ontology: adefovir (C0050175)

Definition (NCI) A nucleoside reverse transcriptase inhibitor analog of adenosine with activity against hepatitis B virus (HBV), herpes virus, and human immunodeficiency virus (HIV).
Definition (CSP) an adenine analog, antiviral agent; used for treating hepatitis, HIV and African swine fever virus infections.
Concepts Pharmacologic Substance (T121) , Nucleic Acid, Nucleoside, or Nucleotide (T114)
MSH C053001
SnomedCT 412073001, 412072006
LNC LP28549-1, MTHU013860
English 9-(2-phosphonylmethoxyethyl)adenine, 9-PMEA, 9-(2-phosphonomethoxyethyl)adenine, PMEA, Phosphonylmethoxyethyl-a, adefovir, adefovir [Chemical/Ingredient], 9-(2-phophonylmethoxyethyl)adenine, ADEFOVIR, 9-(2-Phosphonylmethoxyethyl)adenine, Adefovir (product), Adefovir (substance), Adefovir
Spanish adefovir (producto), adefovir (sustancia), adefovir
Derived from the NIH UMLS (Unified Medical Language System)

Ontology: Preveon (C0754613)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH C106812
English Preveon
Derived from the NIH UMLS (Unified Medical Language System)

Related Topics in Pharmacology

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