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Definition (NCI)
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A sulfur-rich glycosaminoglycan with anticoagulant property. Heparin binds to antithrombin III to form a heparin-antithrombin III complex. The complex binds to and irreversibly inactivates thrombin and other activated clotting factors, such as factors IX, X, XI, and XII, thereby preventing the polymerization of fibrinogen to fibrin and the subsequent formation of clots.
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Definition (NCI_NCI-GLOSS)
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A substance that slows the formation of blood clots. Heparin is made by the liver, lungs, and other tissues in the body and can also made in the laboratory. Heparin may be injected into muscle or blood to prevent or break up blood clots. It is a type of anticoagulant.
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Definition (SPN)
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Enzyme preparations are products that are used in the histopathology laboratory for the following purposes: (1) To disaggregate tissues and cells already in established cultures for preparation into subsequent cultures (e.g., trypsin); (2) To disaggregate fluid specimens for cytological examination (e.g., papain for gastric lavage or trypsin for sputum liquefaction); (3) To aid in the selective staining of tissue specimens (e.g., diastase for glycogen determination).
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Definition (MSH)
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A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.
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Definition (CSP)
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poly(glucosamine sulfate-glucuronic acid); endogenous mucopolysaccharide with antithrombin and lipotropic activities; USP injection is used as an anticoagulant.
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| Concepts |
Pharmacologic Substance
(T121)
, Biologically Active Substance
(T123)
, Carbohydrate
(T118)
|
| MSH |
D006493
|
| SnomedCT |
372877000, 84812008, 96382006 |
| LNC |
LP15998-5, LP16002-5, MTHU003766, MTHU015164 |
| English |
Heparin, Heparinic Acid, heparin preparations (medication), heparin preparations, Heparin [Chemical/Ingredient], Heparin, Unfractionated, Unfractionated Heparin, unfractionated heparin, heparin unfractionated, heparins, heparin, Heparin.unfractionated, Unfractionated heparin, Heparin (product), Heparin (substance), Unfractionated heparin (substance), HEPARIN |
| Swedish |
Heparin
|
| Czech |
heparin
|
| Finnish |
Hepariini
|
| Italian |
Acido eparinico, Eparina non frazionata, Eparina |
| Russian |
GEPARIN, AL'FA-GEPARIN, GEPARINOVAIA KISLOTA, АЛЬФА-ГЕПАРИН, ГЕПАРИН, ГЕПАРИНОВАЯ КИСЛОТА |
| Japanese |
α-ヘパリン, ヘパリン, アルファヘパリン |
| Croatian |
HEPARIN
|
| Polish |
Heparyna
|
| Spanish |
heparina (producto), heparina (sustancia), heparina no fraccionada (sustancia), heparina no fraccionada, heparina, Heparina, Ácido Heparínico |
| French |
Héparine
|
| German |
Heparin, Heparinsäure |
| Portuguese |
Ácido Heparínico, Heparina |
