Antimetabolite Chemotherapy

Aka: Antimetabolite Chemotherapy, Structural Analogue Chemotherapy

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II. Agents

  1. Folic Acid antagonist
    1. Methotrexate
  2. Purine antagonist
    1. Mercaptopurine (6-MP, Purinethol)
    2. Azathioprine (Imuran)
    3. Thioguanine (6-TG)
  3. Pyrimidine antagonist
    1. Fluorouracil (5-FU)
    2. Cytarabine (cytosine arabinoside, ara-C)
    3. Azacitidine (5-azacytidine)

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Ontology: Antimetabolite Chemotherapy (C1516020)

Definition (NCI) Treatment of cancer that utilizes antimetabolite substances to disrupt DNA, RNA, or protein synthesis.
Concepts Pharmacologic Substance (T121)
English Chemotherapy, Antimetabolites, Chemotherapy, Cancer, Antimetabolites, Antimetabolite Chemotherapy
Derived from the NIH UMLS (Unified Medical Language System)

Related Topics in Pharmacology

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