II. Indications
- Suspected Thrombotic Thrombocytopenic Purpura (TTP)
III. Mechanism
- Low ADAMTS13 Enzyme Activity <10% is associated with TTP
IV. Criteria: Assign one point for each positive criteria
- Platelet Count <30,000/uL
- Hemolysis
- No cancer history
- No organ Transplantation history
- Mean Corpuscular Volume (MCV) <90
- Serum Creatinine <2 mg/dl (<177 uMol/L)
- INR <1.5
V. Interpretation: Plasmic Score based on total points from criteria above
- Score 0 to 4
- Low risk (4.3%) of Low ADAMTS13 Enzyme Activity
- Score 5 to 6
- Intermediate risk (56.8%) of Low ADAMTS13 Enzyme Activity
- Score >6
- High risk (96%) of Low ADAMTS13 Enzyme Activity