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Ontology:
Desogestrel
(C0057558)
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Definition (NCI)
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A synthetic progestogen structurally related to levonorgestrel, with progesterone hormone receptor agonistic activity, used as a contraceptive and hormone replacement agent. Upon administration, desogestrel binds intracellular progesterone receptors in progesterone responsive tissue and the resultant complex interacts with DNA causing either gene transcription or gene repression. This eventually leads to an inhibition of gonadotropin releasing hormone (GnRH) secretion from the hypothalamus and a subsequent inhibition of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release. This prevents ovulation and alters the cervical mucus.
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Definition (MSH)
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A synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.
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| Concepts |
Pharmacologic Substance
(T121)
, Hormone
(T125)
, Steroid
(T110)
|
| MSH |
D017135
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| SnomedCT |
116074007, 326306004, 126108008 |
| English |
13-Ethyl-11-methylene-18,19-dinor-17 alpha-pregn-4-en-20-yn-17-ol, Desogestrel, 13 Ethyl 11 methylene 18,19 dinor 17 alpha pregn 4 en 20 yn 17 ol, 18,19-Dinorpregn-4-en-20-yn-17-ol, 13-ethyl-11-methylene-, (17alpha)-, 13-Ethyl-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-17-ol, desogestrel, DESOGESTREL, Desogestrel [Chemical/Ingredient], alpha-pregn-4-en-20-yn-17-ol, 13-Ethyl-11-methylene-18,19-dinor-17, Desogestrel (substance), Desogestrel preparation (product), Desogestrel preparation, Desogestrel product, Desogestrel [dup] (substance), Desogestrel preparation (substance) |
| Swedish |
Desogestrel
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| Czech |
desogestrel
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| Finnish |
Desogestreeli
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| Russian |
DESGESTREL, ДЕСГЕСТРЕЛ |
| Japanese |
デソゲストレル
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| Spanish |
desogestrel (producto), preparado con desogestrel (producto), preparado con desogestrel, desogestrel (sustancia), desogestrel, preparado de desogestrel (sustancia), Desogestrel |
| Italian |
13-Etil-11-metilene-18,19-dinor-17 alfa-pregn-4-en-20-yn-17-ol, Desogestrel |
| Polish |
Dezogestrel
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| French |
Désogestrel
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| German |
Desogestrel
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| Portuguese |
Desogestrel
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Ontology:
Gestodene
(C0061246)
| Concepts |
Pharmacologic Substance
(T121)
, Steroid
(T110)
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| MSH |
C033273
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| SnomedCT |
437760006, 326352006, 395945000 |
| English |
13-ethyl-17-hydroxy-18,19-dinor-17 alpha-pregna-4,15-dien-20-yn-3-one, 17-alpha-ethinyl-13-ethyl-17 beta-hydroxy-4,15-gonadien-3-one, Gestoden, Gestodene, Gestodene [combined oc], Gestodene [combined oral contraceptive], Gestodene (product), gestoden, gestodene, Gestodene [combined oral contraceptive] (product), Pregna-4,15-Dien-20-Yn-3-One, 13-Ethyl-17-Hydroxy-18,19-Dinor-, (17Alpha)-, 13-Ethyl-17-Hydroxy-18,19-Dinor-17Alpha-Pregna-4,15-Dien-20-Yn-3-One, GESTODENE, 18,19-Dinorpregna-4,15-dien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17-alpha)-, Gestodene (substance), Gestodene [combined oral contraceptive] (substance) |
| Spanish |
gestodeno (producto), gestodeno (anticonceptivo oral combinado), gestodeno (anticonceptivo oral combinado) (producto), gestodeno (sustancia), gestodeno |
Ontology:
norgestimate
(C0068992)
| Concepts |
Pharmacologic Substance
(T121)
, Hormone
(T125)
, Steroid
(T110)
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| MSH |
C017576
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| SnomedCT |
326362004, 126115000, 116073001 |
| English |
norgestimate, Norgestimate [combined oc], NORGESTIMATE, norgestimate [Chemical/Ingredient], Norgestimate [combined oc] (product), Norgestimate (substance), Norgestimate preparation (product), Norgestimate preparation, Norgestimate, Norgestimate [combined oc] (substance), Norgestimate preparation (substance) |
| Spanish |
preparado con norgestimato (producto), norgestimato (producto), preparado con norgestimato, norgestimato (anticonceptivo oral combinado), norgestimato (anticonceptivo oral combinado) (producto), norgestimato (sustancia), norgestimato, preparado de norgestimato (sustancia) |
