II. Technique: Tissue Sampling

  1. Fine Needle Aspiration (FNA)
  2. Core Needle Biopsy
  3. Biopsy with Needle Guidance (Image-Guided Biopsy)
  4. Biopsy of Palpable Mass
  5. Incisional Biopsy (Surgical Biopsy)
  6. Sentinel Lymph Node Biopsy

III. Types: Breast Cancer

  1. Ductal Carcinoma Type (Most common)
    1. Ductal Carcinoma In Situ (DCIS)
      1. Basement membrane intact
    2. Invasive Ductal Carcinoma
      1. Broken through wall of duct
  2. Lobular Carcinoma
    1. Lobular Carcinoma In Situ (LCIS)
      1. Not considered a cancer and biopsied lesion will not progress
      2. High risk for future Breast Cancer
    2. Lobular neoplasia

IV. Types: Biomarkers

  1. Estrogen Receptors
  2. Progesterone Receptors
  3. ERBB2 Gene (previously HER2)

V. Grading: Breast Cancer

  1. Grade 1: Well Differentiated
  2. Grade 2: Moderately Differentiated
  3. Grade 3: Poorly Differentiated

VI. Staging: Breast Cancer

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