II. Causes: Common

III. Causes: Less common

  1. See Medication Causes of Dyspepsia
  2. Biliary tract disease
    1. Cholecystitis
    2. Cholelithiasis
  3. Gastroparesis
  4. Pancreatitis
  5. Ischemic bowel disease
  6. Stomach infiltrative disease
    1. Crohn's Disease
    2. Sarcoidosis
  7. Abdominal Malignancy or Mass
    1. Gastric Cancer
    2. Esophageal Cancer
    3. Pancreatic Cancer
    4. Hepatoma
  8. Endocrine abnormalities
    1. Hypercalcemia
    2. Hyperkalemia
  9. Carbohydrate malabsorption
    1. Lactose Intolerance
    2. Sorbitol intolerance
    3. Fructose intolerance
    4. Mannitol intolerance
  10. Systemic disease
    1. Diabetes Mellitus
    2. Thyroid disease
    3. Parathyroid disease
    4. Connective Tissue Diseases
  11. Intestinal Parasites
    1. Giardia
    2. Strongyloides

IV. References

  1. Feldman (1998) Sleisenger and Fordtran's GI, p. 106-8
  2. Bazaldua (1999) Am Fam Physician 60(6): 1773-88 [PubMed]

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Related Studies

Ontology: Dyspepsia (C0013395)

Definition (MEDLINEPLUS)

Nearly everyone has had indigestion at one time. It's a feeling of discomfort or a burning feeling in your upper abdomen. You may have heartburn or belch and feel bloated. You may also feel nauseated, or even throw up.

You might get indigestion from eating too much or too fast, eating high-fat foods, or eating when you're stressed. Smoking, drinking too much alcohol, using some medicines, being tired, and having ongoing stress can also cause indigestion or make it worse. Sometimes the cause is a problem with the digestive tract, like an ulcer or GERD.

Avoiding foods and situations that seem to cause it may help. Because indigestion can be a sign of a more serious problem, see your health care provider if it lasts for more than two weeks or if you have severe pain or other symptoms. Your health care provider may use x-rays, lab tests, and an upper endoscopy to diagnose the cause. You may need medicines to treat the symptoms.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Definition (NCI_CTCAE) A disorder characterized by an uncomfortable, often painful feeling in the stomach, resulting from impaired digestion. Symptoms include burning stomach, bloating, heartburn, nausea and vomiting.
Definition (NCI_NCI-GLOSS) Upset stomach.
Definition (NCI) An uncomfortable, often painful feeling in the stomach, resulting from impaired digestion. Symptoms include burning stomach pain, bloating, heartburn, nausea, and vomiting. Causes include gastritis, gastric ulcer, gastroesophageal reflux disease, pancreatic disease, and gallbladder disease.
Definition (MSH) Impaired digestion, especially after eating.
Concepts Sign or Symptom (T184)
MSH D004415
ICD10 K30 , R10.13
SnomedCT 266505001, 139299007, 249510006, 87548005, 155722007, 196752002, 162031009
English Indigestion, Dyspepsia, Dyspepsias, DYSPEPSIA, INDIGESTION, Indigestion NOS, dyspepsia (diagnosis), dyspepsia, Indigestions, Dyspepsia [Disease/Finding], indigestion, Dyspepsia/indigestion NOS, Indigestion NOS (finding), Dyspepsia (disorder), Dyspepsia, indigestion NOS, Indigestion (finding), Dyspepsia/indigestion, Dyspepsia, NOS, Indigestion, NOS, Dyspepsia (disorder) [Ambiguous]
French DYSPEPSIE, INDIGESTION, Dyspepsie, Indigestion
Portuguese DISPEPSIA, Indisgestão, INDIGESTAO, Dispepsia, Indigestão
Spanish DISPEPSIA, INDIGESTION, indigestión, SAI (hallazgo), indigestión, SAI, dispepsia (trastorno), dispepsia (concepto no activo), dispepsia, indigestión (hallazgo), indigestión, Dispepsia, Indigestión
German DYSPEPSIE, VERDAUUNGSBESCHWERDEN, Dyspepsie, Indigestion, Magenverstimmung, Verdorbener Magen, Verdauungsstörung
Dutch indigestie, Indigestie/dyspepsie, dyspepsie, Dyspepsia, Dyspepsie, Indigestie
Swedish Dyspepsi
Japanese ショウカショウガイ, ショウカフリョウ, 消化不良, 消化障害, 不消化, 消化不良症
Czech dyspepsie, Dyspepsie, Porucha trávení
Finnish Dyspepsia
Italian Indigestione, Dispepsia
Korean 소화불량
Polish Zaburzenia trawienia, Dyspepsja, Niestrawność
Hungarian Dyspepsia, Indigestio
Norwegian Fordøyelsesbesvær, Dyspepsi